Clinical trial · Observational
HRT Versus MOS for Endometrial Preparation Prior to FET in PCOS Patients
Hormone Replacement Therapy Versus Minimal Ovarian Stimulation for Endometrial Preparation Prior to Frozen-thawed Embryo Transfer in Polycystic Ovarian Syndrome Patients
NCT02273791CI-TRIAL-00035506completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Evaluation of endometrial preparation using either hormonal therapy or ovarian stimulation prior to frozen-thawed embryo transfer (FET) in patients with polycystic ovarian syndrome (PCOS)
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Infertility | — | UNRESOLVED | — |
| Polycystic Ovarian Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Estradiol valerate | Drug | — | UNRESOLVED |
| Sequential Clomiphene citrate and Gonadotropin | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- HRT group
- description
- Women will be subjected to HRT using Estradiol valerate before FET
- interventionNames
- Drug: Estradiol valerate
- label
- MOS group
- description
- Women will be subjected to MOS using sequential clomiphene citrate and gonadotropin before FET
- interventionNames
- Drug: Sequential Clomiphene citrate and Gonadotropin
Primary outcomes (1)
- measure
- Clinical pregnancy rate
- timeFrame
- 6 weeks after embryo transfer
- description
- Number of clinical pregnancies (defined as presence of at least one intrauterine gestational sac with fetal pole and cardiac activity on TVS scan at 4-6 weeks after the ET) divided by the number of ET procedures
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 38 Years
Show eligibility criteria text
Inclusion Criteria: * Women with PCOS as defined by the Rotterdam criteria. * Presence of at least 2 cryopreserved good quality cleavage-stage embryo (good quality cleavage-stage embryos display stage-specific cell division, have blastomeres of fairly equal size with few to no cytoplasmic fragments). Exclusion Criteria: * Moderate or severe endometriosis. * Hydrosalpinx. * Uterine abnormalities or myoma. * Previous uterine surgery.
References
Publications (0)
Data not yet available
No reference posted for this study.