Clinical trial · Interventional
Relaxation and Exercise In Lymphoma Patients
A Comparison of Exercise Training With Relaxation Intervention in Lymphoma Patients Post-chemotherapy.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will aim to compare the effects of an Exercise programme and a Relaxation Intervention in lymphoma patients in remission post-chemotherapy on quality of life, cardiovascular fitness, exercise tolerance, muscle strength, psychological status, social well-being and biological markers. Subjects will be recruited from a specialist lymphoma clinic in South West London and randomly allocated to an exercise or a relaxation home programme. The study aims to determine the more effective intervention of the two in relation to the outcome measures. The investigators anticipate that the interventions will result in less adverse events and improved quality of life and physical fitness, and subjects will require less medication, less counseling and cancer nurse specialist care, leading to leading to a reduction in hospital and surgery attendances.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphoma | Lymphoma | ONTOLOGY_EXACT | 0.90 |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Behavioral | — | UNRESOLVED |
| Relaxation | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Exercise Intervention
- description
- Subjects allocated to the Exercise arm will aim to undertake a personal prescribed home exercise programme for half an hour three times a week. Exercises will be progressed at 6 weeks as subjects progress. All exercise sessions will be documented in the logbooks provided. Outcome measures will be assessed at baseline, mid-way (6 weeks) and at the end of intervention (12 weeks).
- interventionNames
- Behavioral: Exercise
- type
- EXPERIMENTAL
- label
- Relaxation Intervention
- description
- Subjects allocated to the Relaxation arm will aim to undertake a guided relaxation programme on a CD for half an hour three times a week. All relaxation sessions will be documented in the logbooks provided. Outcome measures will be assessed at baseline, mid-way (6 weeks) and at the end of intervention (12 weeks).
- interventionNames
- Behavioral: Relaxation
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients with histologically confirmed lymphoma in remission post-chemotherapy 2. Age 18 years or older 3. Ability to give informed consent 4. Good Performance status (ECOG 0-2) 5. Clinically able to carry out exercise training programme on a regular basis Exclusion Criteria: 1. Patients with progressive disease 2. Poor performance status (ECOG status 3 or more) 3. Abnormal resting ECG unexplained by further cardiological investigations 4. Pregnancy 5. Difficulty breathing at rest 6. Persistent cough, fever or illness 7. Cognitive impairment sufficient to limit ability to perform quality of life questionnaires or understand instructions
References
Publications (2)
- DERIVEDHathiramani S, Pettengell R, Moir H, Younis A. Relaxation versus exercise for improved quality of life in lymphoma survivors-a randomised controlled trial. J Cancer Surviv. 2021 Jun;15(3):470-480. doi: 10.1007/s11764-020-00941-4. Epub 2020 Sep 28. PMID 32986231
- DERIVEDHathiramani S, Pettengell R, Moir H, Younis A. Relaxation and exercise in lymphoma survivors (REIL study): a randomised clinical trial protocol. BMC Sports Sci Med Rehabil. 2019 Aug 16;11:17. doi: 10.1186/s13102-019-0127-7. eCollection 2019. PMID 31428434