Clinical trial · Interventional
Decreasing Over Screening and Treatment of Cervical Precancers in Young Women
Randomized Trial to Increase Adherence to Cervical Cancer Screening Guidelines for Young Women
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this study is to prevent over screening and over treatment of young women for cervical precancers, which can result in psychological distress and has been associated with future risk of premature deliveries. Current national guidelines recommend that routine screening be performed at less-frequent intervals and that excisional cervical therapies are discouraged in young women. The objectives of this study are to examine physician- and patient-based interventions designed to decrease over screening and over treatment by increasing adherence to US guidelines for women under 30 years.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ProvAPP + Patient Educational Tool (Tab) | Other | — | UNRESOLVED |
| Provider Mobile Application (ProvAPP) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Provider Mobile Application (ProvAPP)
- description
- Mobile phone application for providers.
- interventionNames
- Other: Provider Mobile Application (ProvAPP)
- type
- EXPERIMENTAL
- label
- ProvAPP + Patient Educational Tool (Tab)
- description
- Patient educational tool; plus the Mobile phone application for providers.
- interventionNames
- Other: ProvAPP + Patient Educational Tool (Tab)
- type
- NO_INTERVENTION
- label
- ProvAPP Control Group
- description
- Clinics in this group are those NOT randomized - receiving no intervention. These clinics will be chosen at random for comparison using Family PACT claims data.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 21 Years
- Maximum age
- 29 Years
Show eligibility criteria text
Inclusion Criteria - Patients: * English or Spanish speaking * Women * Age 21-29 years * History of one or more of the following: abnormal Pap smear, normal Pap smear, no Pap smear, cervical cancer Exclusion Criteria - Patients: * Language other than English or Spanish * Male * Younger than 21 or older than 29 Inclusion Criteria - Clinics: * Family PACT provider * Not a Planned Parenthood affiliate * Located in one of ten identified Southern California study counties * Sends cytology/histology specimens to Quest Diagnostics West Hills * Clinical care visits occurred to at least 200 women age 21-29 years in fiscal year 2011/2012 * Has a calculated average cytology interval of less than 30 months (based on last three years) Exclusion Criteria - Clinics: * Not a Family PACT provider * Planned Parenthood affiliate * Not located in one of ten identified Southern California study counties * Sends cytology/histology specimens to a lab other than Quest Diagnostics West Hills * Clinical care visit occurred to less than 200 women age 21-29 * Has a calculated average cytology interval of more than 30 months
References
Publications (1)
- DERIVEDMoscicki AB, Chang C, Vangala S, Zhou X, Elashoff DA, Dehlendorf C, Sawaya GF, Kuppermann M, Duron Y, Wyand FL, Navarro SK, Thiel de Bocanegra H. Effect of 2 Interventions on Cervical Cancer Screening Guideline Adherence. Am J Prev Med. 2021 May;60(5):666-673. doi: 10.1016/j.amepre.2020.11.015. Epub 2021 Feb 23. PMID 33632649