Clinical trial · Interventional
Prospective Randomised Trial of Exercise and / or Antioxidants in COlorectal Cancer Patients Undergoing Surgery.
The Effects of Exercise on Outcomes in Patients Undergoing Surgery for Colorectal Cancer: a Pilot Prospective Randomised Trial.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Colorectal cancer is the fourth most common cancer in the UK. Surgical resection is the mainstay of curative therapy. With the screening program enabling early detection, surgery plays an important role in treatment strategies. Surgery imparts a significant physiological and psychological stress on cancer patients.Recent research has demonstrated that a fast-track approach utilising regional anaesthesia, early mobilisation and good oral intake can improve outcomes by reducing the physiological stress response to surgery. The primary objective of this study is to determine whether a defined exercise programme can improve recovery and reduce complications after surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control
- description
- Standard pre-operative care
- type
- EXPERIMENTAL
- label
- Exercise
- description
- A 2-4 week low volume, moderate intensity, supervised, one to one, individualised exercise programme. '
- interventionNames
- Behavioral: Exercise
Primary outcomes (1)
- measure
- Length of stay
- timeFrame
- Up to 3 months
- description
- Post-operative hospital length of stay until medically fit for discharge.
Secondary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients with colorectal cancer listed for elective resection surgery who have consented to participate in the study. Exclusion Criteria: * History of unstable angina/unstable coronary artery disease or a heart attack in the previous month * Any heart related disease including but not limited to aortic stenosis, pericarditis or any thromboembolic disease * Severe Infections and fever * Uncontrolled metabolic diseases * Uncontrolled asthma * Acute non-cardiopulmonary disorder that may affect exercise performance or be aggravated by exercise * Resting heart rate of more than 120 BPM * Systolic blood pressure of more than 180 mm Hg or diastolic blood pressure of more than 110 mm Hg * Recent cerebrovascular accident * Pregnancy * Preexisting severe physical disability * Age \<18 years * Unwilling to allow their GP to be informed of their participation in the study
References
Publications (0)
Data not yet available