Clinical trial · Interventional
Effect of Chewing Gum on Postoperative Bowel Function Following Upper GI Tract Cancer Surgery
NCT02260128CI-TRIAL-00015815unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Every patient undergoing surgery in the abdomen will experience temporary paralysis of bowel function. This study evaluates whether chewing gum can reduce the bowel paralysis after surgery in patients undergoing either esophageal resection or whipples procedure. Half the study population will receive chewing gum while the other half will act as control.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Esophagus | — | UNRESOLVED | — |
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Chewing gum | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Gum chewing
- description
- This intervention group will receive chewing gum four times daily following surgery. Each of which they are encouraged to chew for 30 minutes. Gum chewing is terminated when one of the primary end points occurs.
- interventionNames
- Other: Chewing gum
- type
- NO_INTERVENTION
- label
- Control group
- description
- This group will receive the normal postoperative treatment. Occurence of primary end points are registrered.
Primary outcomes (2)
- measure
- Time from surgery to first flatus
- timeFrame
- 7 days
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients undergoing esophageal/cardial resection due to cancer and patients undergoing whipples procedure due to cancer. * Macroradical resection must be accomplished. * Informed consent given. Exclusion Criteria: * Patients WHO fail to follow the study regimen for more than 24 hours. * Patients under the age of 18 years. * Pregnant or beast feeding women.
References
Publications (0)
Data not yet available
No reference posted for this study.