Clinical trial · Observational
Cervical Cancer Screening in HIV Positive and Negative Women in Cambodia
Screening for Prevention of Cervical Cancer in HIV-positive and HIV-negative Cambodian Women Using Direct Visualization With Acetic Acid
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The prevalence of cervical neoplasia in Cambodia is not known. There are no screening programs in place. The investigators plan on introducing a screening program based on WHO criteria and utilizing visualization with acetic acid. Patients who are positive will be offered same-day cryotherapy if indicated or will be referred for biopsy, LEEP and hysterectomy as indicated. The planned patient pool for this study is 1000 women, half of whom will be HIV positive (and thus have a presumed higher incidence of cervical neoplasia).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
| Cervical Neoplasia | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cryotherapy, further biopsy, LEEP, surgery as indicated | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- HIV positive women
- description
- 500 HIV women will be recruited from the hospital's current patient base as well as the community
- interventionNames
- Procedure: cryotherapy, further biopsy, LEEP, surgery as indicated
- label
- HIV negative women
- description
- 500 HIV women will be recruited from the hospital's current patient base as well as the community
- interventionNames
- Procedure: cryotherapy, further biopsy, LEEP, surgery as indicated
Primary outcomes (2)
- measure
- Prevalence of cervical neoplasia in HIV positive women
- timeFrame
- up to 12 months
- description
- 500 HIV positive women will be screened for cervical neoplasia using direct visualization with acetic acid
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 30 Years
- Maximum age
- 49 Years
Show eligibility criteria text
Inclusion Criteria: * female, age 30-49, able to give informed consent Exclusion Criteria: * pregnancy, gross cervical mass, prior cervical cancer, unable to give informed consent, prior complete hysterectomy, allergic to acetic acid
References
Publications (0)
Data not yet available