A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery

Inclusion Criteria:

* 20-70 years old, male or female;
* Subject being diagnosed as having disc degeneration disease, spondylolisthesis, spinal fracture, deformity(degenerative deformity), spinal stenosis, or spinal tumor, has been treated with conservative treatment without relief or getting worse, who is suitable for surgery according to clinic practice.
* Subject is a suitable candidate for implanting investigational products described in study protocols according to investigator's assessment;
* Patient, in the opinion of the Clinical Investigator, is able to understand this clinical investigation and willing to be available for each required study procedure over the study duration.
* Subject has been given voluntary, written informed consent to participate in this clinical investigation and has authorized the transfer of his/her information to study Sponsor.

Exclusion Criteria:

* Patient has a local or systemic infection.
* Patient has had one or more previous non-fusion spinal surgery at the involved level(s).
* Patient without spinal deformity and requires fusion at 3 or more levels.
* Has been previously diagnosed with osteopenia, osteoporosis, or osteomalacia to a degree that spinal instrumentation would be contraindicated
* Has presence of active malignancy
* Has a medical condition with less than 1 year of life expectancy.
* Pregnancy or women in lactation period.
* Is grossly obese, i.e. Body Mass Index≥40.
* Has a diagnosis, which requires postoperative medication or treatment that interferes with fusion, such as steroids, chemotherapy, radiotherapy, growth factor (for more than 3 months), Nonsteroidal Antiinflammatory Drugs(for more than 3 months), and etc.
* Has history of endocrine or metabolic disorder known to affect osteogenesis (e.g. uncontrolled Diabetes with medication, renal osteodystrophy, or osteogenesis imperfect)
* Alcoholic (taking more than 40g/day, equals to 100ml 50°Chinese liquor), smoking more than 40 cigarettes/day, or Drug abuser;
* Is currently participating in another investigational drug or device study.