Clinical trial · Interventional
Exercise and Quality of Life in Leukemia Patients
Effects of Exercise on Patient Reported Outcomes in Newly Diagnosed Adults With Acute Leukemia During Induction Treatment: Exercise and Quality of Life in Leukemia Patients (EQUAL)
NCT02246907CI-TRIAL-00024885EQUALcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the impact of an exercise intervention on patient-reported anxiety, depression, fatigue, and sleep disturbances among acute leukemia patients. The investigators hypothesize that exercise will reduce fatigue in acute leukemia patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Leukemia | Acute Leukemia | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control Group
- description
- The control group will receive standard of care which includes recreational therapy and standard encouragement.
- type
- OTHER
- label
- Exercise
- description
- Participants in this arm will receive standard of care plus exercise for the duration of their inpatient stay for induction chemotherapy.
- interventionNames
- Other: Exercise
Primary outcomes (1)
- measure
- Compare symptoms of fatigue in newly diagnosed acute leukemia patients
- timeFrame
- participants will be followed for the duration of hospital stay, an expected average of 6 weeks
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Newly diagnosed with acute leukemia by pathology report * Admitted for induction chemotherapy within in the previous 96 hours or +/- 3 days from initiation of induction chemotherapy * An expected hospital stay of 3-4 weeks or longer * Participation in the study must be approved by the physician directly responsible for the patient's care while at University of North Carolina -Hospitals * Age \>21 years of age * Willing and able to provide, signed informed consent * Willing and able to use a computer to complete study questionnaires * Ability to understand and speak English Exclusion Criteria: The criteria below will be determined by the patient's physician and a review of the patient's medical history. If any of the exclusion criteria are observed, the patients will be informed and excluded from participating in the study. Participation in this study will involve the same risks as any exercise regimen. Given the potential risks involved, patients will be screened for exclusion based upon the following criteria: * Cardiovascular disease (unless the disease would not compromise the patient's ability to participate in the exercise rehabilitation program) * Acute or chronic respiratory disease that would compromise the patient's ability to participate in the exercise rehabilitation program * Acute or chronic bone, joint, or muscular abnormalities that would compromise the patient's ability to participate in the exercise rehabilitation program * Inability to understand and speak English * Dementia, altered mental status, or any psychiatric condition that would prohibit the understanding or rendering of informed consent * Another active malignancy * Patients will also be excluded if they have active bleeding, acute thrombosis, ischemia, hemodynamically unstable, and uncontrolled pain.
References
Publications (0)
Data not yet available
No reference posted for this study.