Clinical trial · Observational
Observational Study of Early Contact With Palliative Care Unit for Patients Receiving First Line Palliative Chemotherapy With Cancer in Upper Gastrointestinal Canal, or Second Line Palliative Chemotherapy in Patients With Colorectal Cancer - an Open, Randomised Investigator Initiated Trial.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this trial, patients with cancer in the upper gastrointestinal canal who are going to receive first line palliative chemotherapy and patients with colorectal cancer who are going to receive second line palliative chemotherapy will be included. Participating patients will be randomized between early contact with a palliative care unit, or contact with a palliative care unit when needed. The objectives with the trial is to investigate if an early establishment with a palliative care unit will have a positive impact on the patients quality of life, this also applies for the nearest relative, survival, and if a difference in numbers of chemotherapy cycles can be detected.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Tumor in Upper Gastrointestinal Canal or Patients With Colorectal Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Contact with palliative care unit. | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Contact with palliative care unit versus contact when needed.
- interventionNames
- Other: Contact with palliative care unit.
Primary outcomes (1)
- measure
- Quality of Life, such as pain, anxiety.
- timeFrame
- At baseline, every 6th week until death (approximately 1 year). The patients relative will be followed similarly until patients death and then every 12th week for 1 year.
- description
- Evaluation will be performed by different quality of life forms sent to the patient every 6th week, and by telephone contact with a study nurse every 6th week until patients death. The same also applies for the patients nearest relative; quality of life forms will be sent every 12th week for additional 1 year.
Secondary outcomes (1)
- measure
- Survival
- timeFrame
- Approximately 12 months.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with tumor in upper gastrointestinal canal, who is going to start treatment with first line palliative chemotherapy * Patients with colorectal cancer, who is going to start treatment with second line palliative chemotherapy * Signed written informed concent Exclusion Criteria: * Patients with neuroendocrine tumor * Patients with already ongoing chemotherapy * Patients with already established contact with palliative care unit
References
Publications (2)
- DERIVEDBojesson A, Brun E, Eberhard J, Segerlantz M. The ALLAN trial: impact of early home-based palliative care on emergency care and hospitalisation in advanced gastrointestinal cancer patients. Br J Cancer. 2026 Jul;135(2):248-254. doi: 10.1038/s41416-026-03444-8. Epub 2026 Apr 24. PMID 42032200
- DERIVEDBojesson A, Brun E, Eberhard J, Segerlantz M. Quality of life for patients with advanced gastrointestinal cancer randomised to early specialised home-based palliative care: the ALLAN trial. Br J Cancer. 2024 Sep;131(4):729-736. doi: 10.1038/s41416-024-02764-x. Epub 2024 Jul 1. PMID 38951699