Clinical trial · Observational
The Role of Sedation Technique in EBUS-TBNA
Impact of Sedation Technique on the Diagnostic Accuracy of Endobronchial Ultrasound-guided Needle Aspiration (EBUS-TBNA)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
There is a paucity of data concerning the impact of the sedation technique used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) on diagnostic accuracy. The aim of this retrospective study is to compare diagnostic accuracy of EBUS-TBNA in deep and moderate sedation, and to investigate other possible determinants of diagnostic accuracy in three lymph node locations (mediastinal, subcarinal, and hilar). The first consecutive patients at the University Hospital Zurich undergoing EBUS-TBNA for selective sampling in deep sedation are compared with the first consecutive patients in moderate sedation between 2006 and 2014. Diagnoses based on EBUS-TBNA were compared with those on surgical or radiological follow-up.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| General anesthesia for EBUS/TBNA | Procedure | — | UNRESOLVED |
| Moderate Sedation for EBUS/TBNA | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- EBUS-TBNA
- description
- EBUS-TBNA for enlarged mediastinal/hilar lymph nodes
- interventionNames
- Procedure: Moderate Sedation for EBUS/TBNA
- Procedure: General anesthesia for EBUS/TBNA
Primary outcomes (1)
- measure
- Diagnostic accuracy
- timeFrame
- 1-6 months
- description
- Sensitivity, negative predictive value
Secondary outcomes (2)
- measure
- Lymph node morphology
- timeFrame
- 1-6 months
- description
- Impact of lymph node size on diagnostic accuracy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * EBUS-TBNA Exclusion Criteria: * No exclusion criteria
References
Publications (0)
Data not yet available