Clinical trial · Observational
Role of Metabolic Enzymes in Non-Melanoma Skin Cancer
Role of Metabolic Enzymes in Non-Melanoma Skin Cancer: Potential for Informative Biomarkers and Therapeutic Targets
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The researcher can proved that certain compounds play an important role in the prevention of skin cancer. Researcher can use specific compounds, which classified as metabolic enzymes, and lower concentrations and complete absent in skin cancer cells. Researcher can biopsies of normal skin and precancerous or cancerous lesions, and can compare the concentrations of these compounds to determine the difference between the two areas. The result can lead to further understanding of skin cancers and pre-cancers. Because skin cancers and pre-cancers are so common, any knowledge would be very useful for many people in the future and may be used for development of future treatments or prevention strategies.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Skin Cancer | Malignant Skin Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| skin specimen | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- skin specimen
- description
- skin specimen
- interventionNames
- Other: skin specimen
Primary outcomes (1)
- measure
- expression levels of metabolic enzymes in normal skin versus precancerous lesions or skin cancer
- timeFrame
- 1 month
- description
- Overall, compare normal skin versus precancerous lesions or skin cancer from the same individual. Paired tests of samples are selected from the same subjects. * 10 actinic keratosis samples, * 10 basal cell carcinoma samples * 20 squamous cell carcinoma samples * Normal skin control biopsy from the same subject will be collected.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Male or Female are age18 years and older * Have normal skin and a skin lesion of interest * Willing to have skin biopsies on those areas Exclusion Criteria: * Male or Female are under 18 years of age * Pregnant women
References
Publications (0)
Data not yet available