Clinical trial · Interventional
Psychotherapy for Depressed or Anxious Adolescents With Cancer
Open Trial of Behavioral Activation Therapy for Depressed or Anxious Adolescents With Cancer
NCT02232438CI-TRIAL-00019362withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): No participants enrolled.
Summary
Brief summary (as posted)
At present, there are no established treatments for depression or anxiety in adolescents with cancer, creating an important clinical and research gap. Fortunately, there is now substantial evidence documenting the efficacy of psychotherapy in the treatment of depressed and anxious adolescents in the general population.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Depression | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Behavioral activation therapy | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Behavioral activation therapy
- description
- Patients treated with Behavioral activation therapy will improve in mood and anxiety symptoms and psychosocial functioning at the end of the 6 weeks of treatment.
- interventionNames
- Behavioral: Behavioral activation therapy
Primary outcomes (1)
- measure
- Change in Multidimensional Anxiety Scale for Children (MASC 2)
- timeFrame
- baseline, and every two weeks till week 10
- description
- 10 to 15 minutes of mood assessment.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 12 Years
- Maximum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * A primary psychiatric diagnosis of Major Depressive Disorder, Generalized Anxiety Disorder or Adjustment Disorder with Mood or Anxiety features as defined by DSM-IV. * Cancer patients. * Parent consent and child assent to participate for patients younger than 18. Patient consent for subjects 18-21. * Diagnosis of cancer (stage 1-4), but healthy enough to complete study procedures. Exclusion Criteria: * Lifetime history of psychosis or bipolar disorder. * Current suicide risk. * History of substance abuse or dependence in the three months prior to the study. * Patients who have ever failed BAT in the context of cancer. * Receiving other concurrent therapy for same disorder and patients who are receiving effective medication for depression. * Mental retardation. * CNS tumors. * Patients undergoing Stem Cell Transplantation.
References
Publications (0)
Data not yet available
No reference posted for this study.