Clinical trial · Observational
Endoscopic Ultrasound in Detailed T-staging of Upper GI Malignancies in Vitro
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In our era of personalized treatment, both the prognosis and the choice of therapy for upper GI malignancies depend on the staging before any treatment. Most experts recommend EUS (Endoscopic Ultrasound) as the first line for T-staging but the diagnostic accuracy in clinical practice varies in different centers according to the published data. Neither the discrepancy between EUS and histological findings nor the variation between centers well explained. So the investigators designed this prospective study. In the present study, the investigators performed EUS on the resected specimen after surgery before fixation in formalin, evaluated the invasion of the GI wall, and marked the deepest location with sutures. And try to determine the exact accuracy of EUS staging , find the discrepancy between EUS and histologic findings.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastrointestinal Neoplasms | Digestive System Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (4)
- label
- early gastric cancer
- description
- EUS examination on the specimen right after surgery mark the deepest invasive site on the specimen
- label
- Locally Advanced Gastric Cancer
- description
- EUS examination on the specimen right after surgery mark the deepest invasive site on the specimen
- label
- early esophagus cancer
- description
- EUS examination on the specimen right after surgery mark the deepest invasive site on the specimen
- label
- locally advanced esophagus cancer
- description
- EUS examination on the specimen right after surgery mark the deepest invasive site on the specimen
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with upper GI carcinoma * Receive surgery as first treatment Exclusion Criteria: * previous surgery involved the upper GI tract
References
Publications (0)
Data not yet available