Clinical trial · Interventional
A Phase II Trial of CyberKnife Radiosurgery to Perioptic Tumors
A Phase II Study of Fractionated CyberKnife Stereotactic Radiosurgery to Perioptic Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to find out what effects (good and bad) CyberKnife stereotactic radiosurgery has on tumors near the critical structures of the eye (optic apparatus). The investigators hypothesize that hypofractionated stereotactic radiotherapy via the CyberKnife ® can deliver tumor ablating doses of radiation to perioptic lesions safely and effectively while sparing the adjacent optic apparatus and normal brain tissues from receiving damaging doses of radiation.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Tumor, Benign, Optic Nerve | Neoplasm | ALIAS | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CyberKnife Radiosurgery | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- CyberKnife Radiosurgery
- interventionNames
- Radiation: CyberKnife Radiosurgery
Primary outcomes (1)
- measure
- Tumor status
- timeFrame
- 5 years
- description
- To determine the local control rate of patients with perioptic lesions treated with stereotactic CyberKnife radiosurgery.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Perioptic lesion within 2mm of the optic apparatus * Age \>= 21 * KPS \>= 50 * Planning Target Volume (PTV) \<= 6.0 cm in maximal diameter Exclusion Criteria: * Malignant histology * Age \< 21 * KPS \<= 40 * Planning Target Volume (PTV) \> 6.0 cm in maximal diameter * Prior whole brain XRT * Gross total resection
References
Publications (0)
Data not yet available