Clinical trial · Interventional
Magnetic-controlled Capsule Endoscopy vs. Gastroscopy for Detection of Gastric Diseases
Magnetic-controlled Capsule Endoscopy vs. Gastroscopy for Detection of Gastric Diseases: A Prospective Self-controlled Comparative Multicenter Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A new Magnetic-controlled Capsule Endoscopy (MCE) was developed by ANKON and got SFDA's approval in China in 2013. It has recently been evaluated to compare the diagnostic accuracy of MCE with that of standard gastroscopy for gastric diseases in 70 patients with encouraging results (In Press). To further testify the diagnostic accuracy of MCE for both the diffuse and focal diseases in stomach, we performed this single-blinded multi-center prospective study compared MCE with gastroscopy in patients with gastric symptoms and indication for upper GI Endoscopy.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Gastritis | — | UNRESOLVED | — |
| Early Gastric Cancer, | Early Gastric Carcinoma | ALIAS | 0.90 |
| Gastric Diseases, | — | UNRESOLVED | — |
| Gastric Polyps, | — | UNRESOLVED | — |
| Gastric Ulcer, | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MCE | Device | — | UNRESOLVED |
| Standard gastroscopy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- MCE
- description
- patients were assigned to swallow MCE first, followed by the gastroscopy
- interventionNames
- Device: MCE
- type
- ACTIVE_COMPARATOR
- label
- Standard gastroscopy
- description
- patients were assigned to swallow MCE first, followed by the gastroscopy
- interventionNames
- Device: Standard gastroscopy
Primary outcomes (2)
- measure
- Number of subjects diagnosed with gastric diffuse lesions by MCE Versus Standard Gastroscopy
- timeFrame
- 2 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Patients presented with gastric symptoms and ready for the first Upper GI endoscopy * Patients with known focal gastric diseases: gastric ulcer, gastric polyps, early gastric cancer, gastric stromal tumors and so on. * Age of 18 years to 70 years Exclusion Criteria: * Patients with impaired bowel movement from ileus or organic digestive diseases * Patients with known large and obstructing tumors of the upper GI tract * Patients after upper GI surgery or abdominal surgery altering GI anatomy * Patients under full anticoagulation * Patient in poor general condition * Patients using equipment that may be affected by radio transmission * Patients using equipment that may be affected by magnetic field * Pregnancy or suspected pregnancy
References
Publications (3)
- BACKGROUNDLiao Z, Duan XD, Xin L, Bo LM, Wang XH, Xiao GH, Hu LH, Zhuang SL, Li ZS. Feasibility and safety of magnetic-controlled capsule endoscopy system in examination of human stomach: a pilot study in healthy volunteers. J Interv Gastroenterol. 2012 Oct-Dec;2(4):155-160. doi: 10.4161/jig.23751. Epub 2012 Oct 1. PMID 23687601
- BACKGROUNDLiao Z, Gao R, Xu C, Li ZS. Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review. Gastrointest Endosc. 2010 Feb;71(2):280-6. doi: 10.1016/j.gie.2009.09.031. PMID 20152309
- DERIVEDLiao Z, Hou X, Lin-Hu EQ, Sheng JQ, Ge ZZ, Jiang B, Hou XH, Liu JY, Li Z, Huang QY, Zhao XJ, Li N, Gao YJ, Zhang Y, Zhou JQ, Wang XY, Liu J, Xie XP, Yang CM, Liu HL, Sun XT, Zou WB, Li ZS. Accuracy of Magnetically Controlled Capsule Endoscopy, Compared With Conventional Gastroscopy, in Detection of Gastric Diseases. Clin Gastroenterol Hepatol. 2016 Sep;14(9):1266-1273.e1. doi: 10.1016/j.cgh.2016.05.013. Epub 2016 May 20. PMID 27211503