Clinical trial · Observational
Endoscopic Submucosal Dissection Versus Gastrectomy
Long-term Outcomes of Endoscopic Submucosal Dissection Versus Gastrectomy for Early Gastric Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Gastrectomy is curative treatment for early gastric cancer (EGC). Recently, endoscopic submucosal dissection (ESD) has been accepted as standard treatment in selected patients with negligible risk of lymph node metastasis. However, there are limited data regarding the long-term outcomes of ESD in comparison with surgery. This protocol aims to compare overall survival rate, tumor recurrence, development of metachronous cancers after ESD and surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Early Gastric Cancer | Early Gastric Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Surgery group
- description
- Patients who underwent surgery as treatment of early gastric cancer
- interventionNames
- Procedure: Surgery
- label
- ESD group
- description
- Patients who underwent endoscopic submucosal dissection (ESD) as treatment of early gastric cancer, instead of surgery
Primary outcomes (1)
- measure
- Patient's death
- timeFrame
- up to 5 years
Secondary outcomes (2)
- measure
- Tumor recurrence
- timeFrame
- up to 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * differentiated type mucosal cancer without ulceration, regardless of tumor size * differentiated type mucosal cancer with ulceration ≤ 3 cm in diameter * superficial (SM1 \< 500 μm) submucosal cancer ≤ 3 cm in diameter * undifferentiated type mucosal cancer without ulceration ≤ 2 cm in diameter Exclusion Criteria: * early gastric cancer in a remnant stomach * gastrectomy due to metachronous lesions during follow-up period * post-ESD additional surgery due to high risk of lymph node metastasis or the possibility of residual tumor
References
Publications (0)
Data not yet available