Clinical trial · Interventional
The Effect of Walking on Fatigue After Chemotherapy in Patients 65 and Older
A Randomized, Wait-list Controlled Clinical Trial: the Effect of a Physical Activity Program on Fatigue After Potentially Curative Chemotherapy Among Cancer Survivors Age 65 or Older -- PACT (Physical Activity After Chemotherapy)
NCT02191982CI-TRIAL-00029495S-PACTcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will look at the impact of a self-directed walking program on post-chemotherapy survivors experiencing fatigue. It is hypothesized that the walking program will help lessen fatigue.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Fatigue | — | UNRESOLVED | — |
| Geriatric | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Walk With Ease | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention
- description
- This arm will begin the Walk With Ease program after the completion of chemotherapy.
- interventionNames
- Behavioral: Walk With Ease
- type
- ACTIVE_COMPARATOR
- label
- Wait List Control
- description
- The arm will begin the Walk With Ease program three months after completion of chemotherapy.
- interventionNames
- Behavioral: Walk With Ease
Primary outcomes (1)
- measure
- To measure change in fatigue scores between intervention and wait list control arms from baseline to three months.
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Men and women age 65 years and older * Histologically or cytologically confirmed cancer (hematologic or solid) at stage considered amenable to cure as assessed by the treating MD * Within 6 weeks of end of chemotherapy (all participants must have had chemotherapy treatment) * Any radiation received must also be completed prior to randomization (if radiation treatment follows adjuvant chemotherapy, then the patient must be recruited within 6 weeks of end of radiation) * Maintenance hormonal therapy in women with breast cancer is allowed; see exclusion criteria regarding hormonal therapy in males with prostate cancer * Moderate to severe fatigue (\>4 on BFI) * Less than 120 minutes/week of physical activity * English speaking * Signed IRB approved written informed consent * Approval from their treating physician to engage in moderate-intensity physical activity * Patient-assessed ability to walk and engage in moderate physical activity * Willing and able to meet all study requirements. Exclusion Criteria: * Receiving hormonal therapy for prostate cancer * Unable to walk or engage in moderate-intensity physical activity * Have BFI≤3. * Report more than 120 minutes/week of physical activity
References
Publications (0)
Data not yet available
No reference posted for this study.