Clinical trial · Interventional
A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer
Diagnostic Values of Probe-based Confocal Laser Endomicroscopy (pCLE) and Magnifying Narrow Band Imaging (M-NBI) for Early Neoplasms Detection in Esophageal Lugol'S-voiding Lesions.
NCT02182804CI-TRIAL-00046858completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Neoplasms | Esophageal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cellvizio | Device | — | UNRESOLVED |
| Olympus | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Study
- description
- probe-based confocal laser endomicroscopy narrow band imaging with magnification
- interventionNames
- Device: Olympus
- Device: Cellvizio
Primary outcomes (1)
- measure
- Accuracy
- timeFrame
- an expected average of 2 weeks
- description
- Diagnostic performance of the pCLE and M-NBI in Lugol's voiding lesions size larger than 5 millimeters.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Age over 20 years * Having histological-confirmed diagnosis of head and neck cancer * Having no esophageal symptoms Exclusion Criteria: * Having index cancer of nasopharynx * History of esophageal surgery * Having esophageal stricture or obstruction * Having esophageal varices * Known case of esophageal cancer * Uncorrectable coagulopathy and thrombocytopenia * Pregnancy * Thyrotoxicosis * Creatinine clearance less than 30 ml/min * Allergy to iodine or fluorescein.
References
Publications (0)
Data not yet available
No reference posted for this study.