Clinical trial · Observational
Compare the Quality of Life Between Patients With Conduit Diversions or Orthotopic Neobladders
A Prospective and Comparative Study of Health-related Quality of Life (HRQoL) in Patients With Conduit Diversion or Orthotopic Neobladder
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to compare the health-related quality of life (HRQoL) between patients underwent conduit diversion and orthotopic neobladder after radical cystectomy. The investigators plan to use validated HRQoL questionnaires to learn about how the different urinary diversion operations affect the HRQoL of people living with bladder cancer. The findings from this study may help doctors and patients choosing the proper operation type.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| validated health-related quality of life questionnaires | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- bladder cancer, conduit diversion
- description
- new patients with bladder cancer scheduled for radical cystectomy and subsequent conduit diversion
- interventionNames
- Behavioral: validated health-related quality of life questionnaires
- label
- bladder cancer, orthotopic neobladder
- description
- new patients with bladder cancer scheduled for radical cystectomy and subsequent orthotopic neobladder
- interventionNames
- Behavioral: validated health-related quality of life questionnaires
Primary outcomes (1)
- measure
- Change from baseline in HRQoL of bladder cancer patients with different types of urinary diversions
- timeFrame
- Preoperative baseline and 3, 6, 12, 18 months postoperatively
Secondary outcomes (3)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of muscle invasive bladder cancer * Must be scheduled for radical cystectomy and subsequent conduit diversion or orthotopic neobladder * Must be able to provide informed consent * Must be 18 years of age or older * May have had received intravesical neoadjuvant, adjuvant chemotherapy or immunotherapy Exclusion Criteria: * Follow-up data not obtained at Wuhan Union Hospital
References
Publications (0)
Data not yet available