Clinical trial · Observational
Study of Biologic Materials From the Mediastinal Lymph Nodes From Patients With Lung Disease.
Evaluation of the Mediastinal Lymph Nodes With Endobronchial-Guided Transbronchial Needle Aspiration in Individuals With Lung Diseases
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study was terminated due to lack of funding.
Summary
Brief summary (as posted)
The purpose of this protocol is to obtain biologic materials from the mediastinal lymph nodes from patients with lung disease and mediastinal lymph node involvement in order to: (1) develop a better understanding of the cause and development of lung disorders involving the mediastinal lymph nodes; (2) identify biologic parameters that help diagnose and predict the behavior of human lung diseases; and (3) identify individuals who will be suitable candidates for other protocols such as those involving investigational new drugs.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Inflammation | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Lung Disease | — | UNRESOLVED | — |
| Sarcoidosis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Patients with lung disease
- description
- General admission criteria for this project will require at least one of the following: (1) symptoms consistent with pulmonary disease with mediastinal lymph node involvement ; (2) chest X-ray and chest CT scan consistent with lung disease and mediastinal lymph node involvement; (3) Individuals with a lung biopsy consistent with lung disease and presenting with enlarged mediastinal lymph nodes; and (4) patients with diseases of organs with known association with lung disease and mediastinal lymph node involvement.
Primary outcomes (1)
- measure
- Evidence that is consistent with lung disease and presentation of enlarged mediastinal lymph nodes
- timeFrame
- 24 Hours
- description
- Bronchoscopy with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Must provide informed consent * Males and females, age 18 years and older * Lung disease proven by at least one of the following: 1. symptoms consistent with pulmonary disease 2. chest X-ray and chest CT and/or PET CT scan consistent with lung disease and mediastinal lymph node involvement 3. lung biopsy consistent with lung disease known to involve mediastinal lymph nodes 4. patients with diseases of organs with known association to lung disease and mediastinal lymph node involvement. * Undergoing fiberoptic bronchoscopy with EBUS-TBNA as dictated by their standard clinical care Exclusion Criteria: * Patient refuses consent. * Any history of allergies to xylocaine, lidocaine, versed, valium, atropine, or any local anesthetic will not be included in the study * Individuals who cannot tolerate general anesthesia or moderate sedation and analgesia
References
Publications (0)
Data not yet available