Clinical trial · Interventional
Comparison on the Efficacy of Endoscopic Snare Papillectomy With or Without Submucosal Injection
A Prospective Comparative Study of Papillectomy
NCT02165852CI-TRIAL-00019488completedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Because the ampulla of Vater is strategically located at the confluence of the pancreatic and common bile ducts, endoscopic resection of papillary neoplasms may be technically different from endoscopic mucosal resection in other parts of the gastrointestinal tract. The best method of endoscopic ablation and the optimal period for surveillance have not been established.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ampulla of Vater Adenoma | Ampulla of Vater Adenoma, Intestinal-Type | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Papillectomy with injection | Procedure | — | UNRESOLVED |
| Papillectomy without injection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Papillectomy without injection
- description
- Conventional snaring mucoal resection without submucosal injection
- interventionNames
- Procedure: Papillectomy without injection
- type
- ACTIVE_COMPARATOR
- label
- Papillectomy with injection
- description
- Conventional mucosal resction method following injeciton of diluted epinephrine mixture.
- interventionNames
- Procedure: Papillectomy with injection
Primary outcomes (1)
- measure
- complete resection
- timeFrame
- one month
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * ampulla of Vater adenoma * no uncontrolled coagulopathy Exclusion Criteria: * adenocarcinoma of ampulla of Vater * uncontrolled coagulopathy * refusal to this study
References
Publications (1)
- DERIVEDHyun JJ, Lee TH, Park JS, Han JH, Jeong S, Park SM, Lee HS, Moon JH, Park SH. A prospective multicenter study of submucosal injection to improve endoscopic snare papillectomy for ampullary adenoma. Gastrointest Endosc. 2017 Apr;85(4):746-755. doi: 10.1016/j.gie.2016.08.013. Epub 2016 Aug 24. PMID 27566056