Clinical trial · Interventional
Contrast The Role of Avitene And OK-432 in Reducing Seroma Formation After Axillary Lymphadenectomy for Breast Cancer
Contrast The Role of Microfibrillar Collagen Hemostat Flour（Avitene） And OK-432 （Sapylin）in Reducing Seroma Formation After Axillary Lymphadenectomy for Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
After Axillary lymphadenectomy for breast cancer there are not few patients showed seroma formation and it can not be ignored.Investigators aimed to study two new methods of application of Microfibrillar Collagen Hemostat Flour and OK-432 to reduce seroma formation and to verify the efficacy and safety of these two applications.Try to prove them as beneficial supplements for axillary lymphadenectomy of breast cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Drainage | — | UNRESOLVED | — |
| Postoperative Complications | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Avitene | Drug | — | UNRESOLVED |
| axillary drainage | Behavioral | — | UNRESOLVED |
| reexamine | Other | — | UNRESOLVED |
| Sapylin | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Avitene,Drainaging,reexamine
- interventionNames
- Drug: Avitene
- Behavioral: axillary drainage
- Other: reexamine
- type
- EXPERIMENTAL
- label
- Sapylin,Drainaging,reexamine
- interventionNames
- Drug: Sapylin
- Behavioral: axillary drainage
- Other: reexamine
- type
- ACTIVE_COMPARATOR
- label
- Drainaging,reexamine
- interventionNames
- Behavioral: axillary drainage
- Other: reexamine
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients volunteered for the study and signed informed consent； 2. Preoperative biopsy or intraoperative sentinel lymph node biopsy confirmed axillary lymph node metastasis and need axillary lymphadenectomy 3. No penicillin allergy 4. No blood system diseases 5. No rheumatic heart disease 6. No history or family history of asthma 7. No history of axillary surgery Exclusion Criteria: 1. A history of severe hypertension 2. A history of diabetes 3. Undergoing anticoagulant therapy or anticoagulant therapy drug withdrawal less than a year 4. BMI\>30 5. Can not accept telephone follow-up or can not go to the hospital for subsequent inspection treatment
References
Publications (0)
Data not yet available