Clinical trial · Interventional
The Changes of Ryodoraku and HRV After PPI Treatment in GERD Patients
NCT02149914CI-TRIAL-00016119unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Gastroesophageal reflux disease(GERD) mainly related to the reflux of stomach content induced by the dysfunction of lower esophageal sphincter. Proton pump inhibitors (PPI) can effectively block gastric acid secretion but the drug reactions and the degree of improvement in symptoms are sometimes unpredictable. The aim of this study is to investigate the association between the clinical efficacy of PPI in patients with GERD and the personal physical status by Ryodoraku and ANSWatch.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Barrett's Esophagus | — | UNRESOLVED | — |
| Non-erosive Reflux Disease | — | UNRESOLVED | — |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ANSWatch | Device | — | UNRESOLVED |
| GerdQ | Other | — | UNRESOLVED |
| PPI | Drug | — | UNRESOLVED |
| Ryodoraku | Device | — | UNRESOLVED |
| UGI endoscopy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- PPI treatment
- description
- Patients with GERD would be assessed by ANSWatch. Ryodoraku, UGI endoscopy, and GerdQ before taking PPIs and after taking PPI 20mg tablet by mouth everyday for 4 weeks.
- interventionNames
- Device: Ryodoraku
- Device: ANSWatch
- Device: UGI endoscopy
- Other: GerdQ
- Drug: PPI
Primary outcomes (1)
- measure
- gastroesophageal reflux disease questionnaire
- timeFrame
- four weeks
- description
- To assess the severity of GERD
Secondary outcomes (1)
- measure
- Upper gastrointestinal endoscopy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * male or female * age of 20-75 years * patients with GERD who have to receive PPIs for four weeks Exclusion Criteria: * Suffering from peptic ulcer, gallstones, cancer, and Barrett's esophagus * previously underwent the esophagus, stomach or duodenum surgery * Lactating women or pregnant women
References
Publications (0)
Data not yet available
No reference posted for this study.