Clinical trial · Observational
Collaborative Assessment of Pediatric Transverse Myelitis: Understand, Reveal, Educate or CAPTURE Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients and families are invited to participate in an online registry and data repository specifically for patients with transverse myelitis (TM) or acute flaccid myelitis (AFM). The data generated in this study will come from surveys, interviews, review of medical records. Data from this study will be utilized to guide future clinical trials for children with an acute case of TM or AFM. Parents and school aged children will complete an online survey 7 banks of questions. Each bundle of survey topics have 7-10 questions. We will have both the parent and child complete a outcomes based survey within 6 months of diagnosis and invite to participate every 4 months until study end in 2024.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Flaccid Paraplegia, Complete, Acute | — | UNRESOLVED | — |
| Flaccid Paraplegia, Incomplete, Acute | — | UNRESOLVED | — |
| Myelitis, Transverse | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- myelitis, transverse or acute flaccid myelitis
- description
- Observational study with online survey participation highlighting outcomes recovery. The surveys can be completed by the child and parent, or if too young to participate, parent only. The survey asks how the child is doing after hospitalization within 6 months of diagnosis, and every 4 months until study end in 2024.
Primary outcomes (1)
- measure
- Patient and parent reported symptoms of recovery
- timeFrame
- up to one year post symptom onset
- description
- each parent /guardian and child will fill out a questionnaire examining how you feel about your ability to move and your emotions. This is completed at 3,6,and 12 months after symptoms are diagnosed.
Secondary outcomes (1)
- measure
- ASIA scale
- timeFrame
- up to one year after symptom diagnosis
- description
- We will measure the motor (movement) and sensory (touch) of the child above and below the spinal lesion. This is completed at 3 time points 3,6,and 12 months post symptom onset. For the secondary outcomes, the family needs to be able to travel to 1 of the 5 centers listed in the study.
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 17 Years
Show eligibility criteria text
Inclusion Criteria for the registry: * Diagnosis of transverse myelitis (TM) or acute flaccid myelitis (AFM) * Patient is within 6 months of symptom onset * Ability of patent or legal guardian is able to provide informed consent * Ability of a child 10 or older able to provide assent * Access to the internet Exclusion Criteria for the registry: * Inability to provide appropriate consent or assent * Diagnosis of multiple sclerosis, neuromyelitis optica, or neuromyelitis optica spectrum disorder
References
Publications (0)
Data not yet available