Clinical trial · Interventional
Perioperative Inflammation and Breast Cancer Outcome
Suppression of Inflammation by Using NSAIDs During Peri-operative Period Can Affect the Prognosis of Breast Cancer.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
It is increasingly recognized the NSAIDS (nonsteroidal antiinflammatory drug) might prevent the several cancers. In breast cancer, the role of NSAIDS (nonsteroidal antiinflammatory drug) has been suggested.However, there was no consistent results. surgery is main cause of inflammation for cancer patients. Therefore, we want to know the association between prevention of perioperative inflammation with NSAIDS and breast cancer outcomes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| NSAIDS (ketorolac and ibuprofen) | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control arm
- description
- no medication or acetaminophen
- type
- EXPERIMENTAL
- label
- NSAIDS (ketorolac intravenous, ibuprofen)
- description
- ketorolac IV (just before surgery) and ibuprofen for 1 weeks
- interventionNames
- Drug: NSAIDS (ketorolac and ibuprofen)
Primary outcomes (1)
- measure
- disease free survival
- timeFrame
- 5 years
Secondary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Breast cancer patients who took the surgery Exclusion Criteria: * underlying medical disease (major heart disease, lung disease, coagulopathy) * major psychologic disease (major depression, schizophrenia, manic disorder) * pregnancy * rheumatic disease patients
References
Publications (0)
Data not yet available