Clinical trial · Interventional
Phase 1 Trial of Chlorogenic Acid in Patients With Advanced Cancer
Phase 1 Trial Evaluating Tolerability and Pharmacokinetics of Chlorogenic Acid for Injection in Patients With Advanced Cancer
NCT02136342CI-TRIAL-00015876terminatedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study site change
Summary
Brief summary (as posted)
The purpose of the study is to explore if chlorogenic acid is safe in patients with cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Cancer | Malignant Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| chlorogenic acid | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- chlorogenic acid
- interventionNames
- Drug: chlorogenic acid
Primary outcomes (1)
- measure
- Number of adverse events
- timeFrame
- within the first 60 days after the first dose of chlorogenic acid
Secondary outcomes (4)
- measure
- dose-limiting toxicity
- timeFrame
- within the first 30 days after the first dose of chlorogenic acid
- measure
- maximum tolerated dose
- timeFrame
- within the first 30 days after the first dose of chlorogenic acid
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * advanced cancer with no effective treatment * Karnofsky performance status no less than 70 * adequated organ function * informed consent Exclusion Criteria: * allergic to chlorogenic acid * persistent toxicities from previous treatment (no less than grade 2)
References
Publications (0)
Data not yet available
No reference posted for this study.