Clinical trial · Interventional
Protein-Sparing Modified Fast Intervention for Weight Loss in Obese Endometrial Cancer Survivors
A Pilot Study of a Protein-Sparing Modified Fast for Weight Loss in Obese Endometrial Cancer Survivors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This pilot clinical trial studies protein-sparing modified fast (PSMF) intervention for weight loss in obese endometrial cancer survivors. The PSMF is a diet that is very low in carbohydrates and calories, designed to induce fast, safe weight loss. The diet consists of only lean meats (beef, pork, poultry, and seafood) in amounts adequate to meet protein requirements based on the individual's body weight. The PSMF may help endometrial cancer survivors achieve significant weight loss, reduce the risk of chronic disease, and improve quality of life.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
| Obesity | — | UNRESOLVED | — |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Average score of Obesity and Weight-Loss Quality of Life Questionnaire | Other | — | UNRESOLVED |
| Dietary Education | Other | — | UNRESOLVED |
| Dietary Intervention | Dietary Supplement | — | UNRESOLVED |
| Informational Material | Other | — | UNRESOLVED |
| Weight Maintenance | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Supportive Care (PSMF)
- description
- Participants will take part in a Protein-Sparing Modified Fast (PSMF) Intervention for weight loss. Participants will undergo a dietary intervention high in protein for 6 weeks or until they have loss 15% of their body weight. This intervention will be followed by weight maintenance in which participants reintroduce non-starchy vegetables to their diet. At this time participants will also receive informational material and dietary education which teaches participants how to read nutrition labels and calculate carbohydrate loads in foods. Participants are given the Obesity and Weight-Loss Quality of Life Questionnaire to survey the impact of the intervention
- interventionNames
- Dietary Supplement: Dietary Intervention
- Other: Informational Material
- Other: Dietary Education
- Dietary Supplement: Weight Maintenance
- Other: Average score of Obesity and Weight-Loss Quality of Life Questionnaire
Primary outcomes (2)
- measure
- Mean Weight loss assessed with the digital scale
- timeFrame
- Baseline up to 6 months
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Previous diagnosis of endometrial cancer, successfully treated through surgery * Body mass index (BMI) \> 30 kg/m\^2 * \> 8 weeks removed from surgery to treat endometrial cancer Exclusion Criteria: * No previous diagnosis of endometrial cancer * BMI \< 30 kg/m\^2 * Any history of cardiovascular, kidney, or liver disease * Using medication to treat diabetes * History of cardiac arrhythmias * Inability to comply with follow up regimen * Inability to read or speak English * Abstention from meat and other animal products
References
Publications (0)
Data not yet available