Clinical trial · Interventional
Study of the Application of CPAP to Reduce Complications and Improve Lung Cancer Ablation Radiofrequency Treatment
Application of CPAP to Reduce Complications and Improve Treatment of Radiofrequency Ablation of Lung Cancer Under Conscious Sedation. A Randomized Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The project aims to study whether the application of a continuous positive airway pressure (CPAP) of 4 cm water vapor is a safe method in pulmonary radiofrequency intervention (PRF) lung cancer under conscious sedation compared with placebo. And, assess whether CPAP prevents atelectasis formation and consequently reduces the potential complications of PRF and improves procedural success
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Atelectasis | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| RESMED AUTOSET S9 | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- CPAP +4 cm H2O
- description
- CPAP +4 cm H2O pressure using ResMedTM face mask
- interventionNames
- Device: RESMED AUTOSET S9
- type
- SHAM_COMPARATOR
- label
- ShamCPAP
- description
- shamCPAP using ResMedTM CPAP face mask modified for technical sham
- interventionNames
- Device: RESMED AUTOSET S9
Primary outcomes (1)
- measure
- Number of Participants with Adverse Events as a Measure of Safety
- timeFrame
- thirty days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * male and female aged 18 years and older * Patient with a scheduled intervention for ablation of pulmonary malignant tumor with radiofrequency . * Patient able to undergo tests and examinations required by the study. Exclusion Criteria: * Patients with CPAP intolerance test. * Patients with progressive disease in which local treatment is not applicable * Patients with intercurrent process (pleural effusion, pneumonia, ...). * Patient unable to understand the proceedings. * Pregnancy or breastfeeding.
References
Publications (1)
- DERIVEDCarrero-Cardenal E, Vollmer-Torrubiano I, Torres-Lopez M, Martin-Barrera G, Casanovas-Mateu G, Tercero-Machin FJ, Paez-Carpio A, Fabregas-Julia N, Valero-Castell R. Continuous positive airway pressure is unsafe for radiofrequency ablation of lung cancer under sedation: a randomised controlled trial. Insights Imaging. 2024 Jun 20;15(1):153. doi: 10.1186/s13244-024-01721-9. PMID 38900225