Clinical trial · Observational
Meaning-Centered Counseling for Chinese Patients Who Are Being Treated for Advanced Cancer
Adaptation of Individual Meaning-Centered Psychotherapy for Chinese Immigrant Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to modify a type of counseling called "Individual Meaning Centered Psychotherapy" to meet the needs of Chinese cancer patients. Many cancer patients use counseling or other resources to help cope with the emotional burden of their illnesses. Counseling often helps them cope with cancer by giving them a place to express their feelings. "Meaning-Centered" counseling aims to teach cancer patients how to maintain or even increase a sense of meaning and purpose in their lives, despite cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Cancer | Malignant Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Adaptation of IMCP for Chinese Immigrant Cancer Patients | Behavioral | — | UNRESOLVED |
| In-depth Patient Interviews | Behavioral | — | UNRESOLVED |
| Individual Meaning-Centered Psychotherapy for Chinese (IMCP-Ch) (For Phase 3 and Phase 4) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Chinese patients with advanced cancer
- description
- IMCP intervention to be culturally \& linguistically tailored for Chinese cancer patients. This study will be carried out in 3 phases: 1) formative research \& 2) adaptation. For this application we will continue the formative research (phase 1) by conducting 20 to 30 indepth interviews with Chinese immigrants with advanced cancer to inform the adaptation of the intervention. Results of the patient in-depth interviews will inform how to adapt the IMCP process \& session themes to reflect the needs of the community. In the adaptation phase (phase 2) the Breitbart IMCP research team (including Drs. Breitbart, Lichtenthal, \& Applebaum), Drs. Leng, Gany, \& Ms. Huang will discuss a priori adaptations to the intervention. Potential changes to the process \& content will be discussed. Adaptations will be incorporated in a modified IMCP-Ch treatment manual, therapist checklist/outline \& Treatment Integrity Coding Manual. PHASE 3, 4 Conduct feasibility study of IMCP-Ch for Chinese cancer patients.
- interventionNames
- Behavioral: In-depth Patient Interviews
- Behavioral: Adaptation of IMCP for Chinese Immigrant Cancer Patients
- Behavioral: Individual Meaning-Centered Psychotherapy for Chinese (IMCP-Ch) (For Phase 3 and Phase 4)
Primary outcomes (1)
- measure
- adapt the Individual Meaning-Centered Psychotherapy (IMCP)
- timeFrame
- 2 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: Phases 1 and 2: Interview Inclusion Criteria (per self-report): * Non-US born; * Of Chinese descent; * Age 21 years through 80 years; * Language spoken: Mandarin and/or English * Diagnosis of Stage IV cancer (any type). Phase 3: * Stage III or IV cancer (per self-report or on the MSKCC EMR). If traditional staging does not apply (i.e. for leukemia), we can allow patient deemed by provider to have poor prognosis/roughly equivalent to Stage III or IV to be referred. * Age 18 or older * Of Chinese descent * Mandarin-speaking * Have an estimated life expectancy of at least 6 months (per self-report or on the MSKCC EMR) * Resides in New York State or New Jersey Phase 4: * Stage III or IV cancer (per self-report or on the MSKCC EMR). If traditional staging does not apply (i.e. for leukemia), we can allow patient deemed by provider to have poor prognosis/roughly equivalent to Stage III or IV to be referred. * Age 18 or older * Of Chinese descent * Mandarin-speaking * Have an estimated life expectancy of at least 6 months (per referring physician assessment or on the MSKCC EMR) * Resides in New York State or New Jersey Exclusion Criteria: Phases 1 and 2: * Presence of cognitive impairment disorder (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or data collection. The Chinese version of the Mini Mental State Examination (MMSE) (46) will be used as a cognitive screening tool. Patients with MMSE scores below 20 will be excluded. For English speaking patients we will use the English version of the MMSE. * Has a household member who has already participated (or agreed to participate). Phase 3: * Previous participation in Phases 1 or 2 of the study * Unable/unwilling to use or no access to a telehealth platform (i.e., telephone or videoconference) * For participants who express interest in RSMI, unable/unwilling to use Zoom videoconferencing platform * Unable or unwilling to commit to up to 16 weeks to complete 6-session intervention and follow-up assessments * Major psychiatric illness or cognitive impairment that in the judgment of study investigators or study staff would preclude study participation * Patients diagnosed with primary brain tumors (per self-report or on the MSKCC EMR), as they may have difficulty completing the intervention and answering questionnaires * Undergoing hematopoietic stem cell transplantation (HSCT) (per self-report or on the MSKCC EMR) * Currently in psychotherapeutic treatment (patients being treated with psychotropic medications will not be excluded, as long as they are not in psychotherapy; per self report) Phase 4: * Previous participation in Phases 1, 2, or 3 of the study * Unable/unwilling to use or no access to the Zoom videoconferencing platform (required for RSMI) * Unable or unwilling to commit to up to 16 weeks to complete 6-session intervention and follow-up assessments * Major psychiatric illness or cognitive impairment that in the judgment of study investigators or study staff would preclude study participation * Patients diagnosed with primary brain tumors (per self-report or on the MSKCC EMR), as they may have difficulty completing the intervention and answering questionnaires * Undergoing hematopoietic stem cell transplantation (HSCT) (per self-report or on the MSKCC EMR) * Currently in psychotherapeutic treatment (patients being treated with psychotropic medications will not be excluded, as long as they are not in psychotherapy; per self report)
References
Publications (2)
- DERIVEDLui F, Chen RY, Chang F, Jiang R, Yang K, Zhao C, Gany F, Leng J. Lessons from the field: culturally grounded approaches to recruiting Chinese American immigrant cancer patients to psycho-oncology trials. Support Care Cancer. 2026 Jul 4;34(7):733. doi: 10.1007/s00520-026-10932-3. PMID 42400659
- DERIVEDLui F, Gany F, Espinosa A, Riobo C, Chang F, Narang B, Rodriguez A, Gonzalez J, Niu Y, Chen RY, Jiang R, Leng J. INTERPRETing to increase access to PSYcho-oncology care (INTERPRET-PSY) for cancer patients with limited English proficiency: study protocol for a pilot randomized controlled trial. Pilot Feasibility Stud. 2026 Jan 29;12(1):31. doi: 10.1186/s40814-026-01770-5. PMID 41612461