Clinical trial · Observational
Germ Cell Tumor and Testicular Tumor DNA Registry
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without these tumors. This study will help us learn more about the prevention, diagnosis, treatment and outcome of these tumors. Studying relatives of patients and people unrelated to patients with GCT and other testicular tumors will help us understand why some people get these tumors and why some people don't.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Germ Cell Tumor | Germ Cell Tumor | ONTOLOGY_EXACT | 0.90 |
| Testicular Tumor | Testicular Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Questionnaires | Behavioral | — | UNRESOLVED |
| sample of blood or saliva | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- A: suspicion of germ cell tumor and/or a testicular mass
- description
- patients with testicular GCTs and non-GCT testicular tumors, extragonadal male GCTs, and female GCTs,
- interventionNames
- Behavioral: Questionnaires
- Other: sample of blood or saliva
- label
- B: family members of Group A
- description
- relatives of patients with GCTs or testicular tumors
- interventionNames
- Behavioral: Questionnaires
- Other: sample of blood or saliva
- label
- C: healthy controls unrelated to Group A or B
- description
- healthy controls who are unrelated to Groups A or B and do not have a personal history of cancer nor a family history of GCT or non-GCT testicular tumors
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Case Cohort * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must have a diagnosis or suspicion of germ cell tumor and/or a testicular mass Family Member Cohort * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must be a blood relative of the proband. Family members of probands are eligible. These individuals need not have a diagnosis of GCT-TT, as they will be used for segregation analysis of suspected variants found in the proband. Control Cohort * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must not have a personal history of cancer, with the exception of non-melanoma skin cancer, AND * Must not have a family history of germ cell tumor or testicular tumor AND * Must not be a blood relative of controls enrolled in this study Exclusion Criteria:
References
Publications (0)
Data not yet available