Clinical trial · Observational
Combined Liver and Right Lung Resection for Colorectal Metastases by Means of J-shaped Thoracophrenolaparotomy
NCT02090816CI-TRIAL-00014044completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether J-shaped thoracophrenolaparotomy is effective in the surgical treatment of simultaneous liver and right lung metastases from colorectal cancer
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer Liver Metastasis | — | UNRESOLVED | — |
| Multiple Pulmonary Nodules | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgery of liver and lung | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Surgery of liver and lung
- description
- Patients carriers of both liver and right lung metastases in the same time
- interventionNames
- Procedure: Surgery of liver and lung
Primary outcomes (1)
- measure
- Number of metastases removed
- timeFrame
- Baseline: date of surgical operation
- description
- Evaluation of the resectability of whole metastases in liver and right lung in the same operation by means of the same surgical incision (J-shaped thoracophrenolaparotomy)
Secondary outcomes (2)
- measure
- Number of patients that received interventional treatments after surgery
- timeFrame
- Participants will be followed from the baseline (date of surgery) to 90 days after the operation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Controlled primary disease; * No extrahepatic lesion other than resectable pulmonary metastases at preoperative investigation; * No lymph-node metastases except for those eventually present at the hepatic hilum; * Disregarding number and distribution of liver metastases, technical resectability leaving at least a remnant liver volume of at least 40% of the total liver volume (calculated excluding the tumoral volume) featured by preserved inflow, outflow and biliary drainage. Zero mm free margin was considered acceptable in case of contact or close adjacency (\< 5 mm) with 1st or 2nd order portal pedicles and/or major hepatic veins at their caval confluence; * Disregarding number and distribution of lung metastases, all of the detected nodules could be completely removed preserving enough functioning remnant lung based on the results of the preoperative cardio-pulmonary functional tests; * Patients eligible for a J-shaped thoracophrenolaparotomy because carrier of liver metastases located at the caval confluence, or in the paracaval portion of segment 1 or in the upper right segments (4 superior, 7 and 8), or presenting strong-adhesion or infiltration of the diaphragm. Exclusion Criteria: * Patients not suitable for surgery
References
Publications (0)
Data not yet available
No reference posted for this study.