Clinical trial · Interventional
A Pilot Study on Usefulness of Probe-based Confocal Laser Endomicroscopy Targeted Gastric Biopsy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to conduct a study on genetic pathology, obtaining of pure cancer tissues is mandatory. Although the endoscopy with biopsy has been a gold standard for diagnosing gastric cancer, percentage of cancer cells in biopsy samples is usually 30% or less. Recently, confocal laser endomicroscopy has been introduced for real-time histopathologic diagnosis in various cancers. The investigators aim to evaluate that biopsy using probe-based confocal laser endomicroscopy will increase the percentage of cancer cells in biopsy samples.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Probe-based confocal laser endomicroscopy | Procedure | — | UNRESOLVED |
| White light endoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Probe-based confocal laser endomicroscopy
- interventionNames
- Procedure: Probe-based confocal laser endomicroscopy
- type
- ACTIVE_COMPARATOR
- label
- White light endoscopy
- interventionNames
- Procedure: White light endoscopy
Primary outcomes (1)
- measure
- The percentage of cancer cells in biopsy samples
- timeFrame
- After 3 days from the end of the endoscopic submucosal dissection
- description
- The percentages of cancer cells in biopsy samples according to the method of endoscopic method, probe-based confocal laser endomicroscopy versus white light endosocpy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age, between 20 and 80 2. Initial-onset gastric cancer which would be treated with surgery Exclusion Criteria: 1. Previous subtotal gastrectomy 2. Pregnancy or breast milk feeding 3. Active infection 4. Significant cardiopulmonary disease 5. Active hepatitis or severe hepatic dysfunction 6. Severe renal dysfunction 7. Severe bone marrow dysfunction 8. Severe neurologic or psychotic disorder
References
Publications (0)
Data not yet available