Clinical trial · Observational
Kidney Cancer DNA Registry
NCT02087852CI-TRIAL-00107722recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This registry will help us develop better methods of: * Preventing these cancers * Diagnosing these cancers * Treating these cancers
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Cancer | Kidney Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood draw | Other | — | UNRESOLVED |
| Epidemiologic Questionnaire | Behavioral | — | UNRESOLVED |
| Family History Questionnaire (when applicable) | Behavioral | — | UNRESOLVED |
| salvia for germline DNA | Other | — | UNRESOLVED |
| the Kidney Cancer Questionnaire | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- kidney cancer patients receiving care at MSKCC
- description
- Participation will consist of completing the Kidney Cancer Questionnaire Family History Questionnaire and complete the Epidemiologic Questionnaire (when applicable,), and providing a blood sample and saliva sample for germline DNA. In cases where tissue samples from surgically derived tumor specimens are obtained these will used to determine genetic alterations related to cancer predisposition or pathogenicity.
- interventionNames
- Other: salvia for germline DNA
- Behavioral: the Kidney Cancer Questionnaire
- Behavioral: Family History Questionnaire (when applicable)
- Other: Blood draw
- Behavioral: Epidemiologic Questionnaire
- label
- relatives of patients with kidney cancer
- description
- Participation will consist of completing the Kidney Cancer Questionnaire Family History Questionnaire (when applicable,), and providing a saliva sample for germline DNA. In cases where tissue samples from surgically derived tumor specimens are obtained these will used to determine genetic alterations related to cancer predisposition or pathogenicity.
- interventionNames
- Other: salvia for germline DNA
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Kidney Cancer Case Cohort: * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must have a diagnosis or suspicion of kidney cancer Family Member Cohort: * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must be a blood relative of the proband. Family members of probands including mother, father, sisters, brothers, half-sisters, half-brothers, daughters, sons, grandmothers, grandfathers, as well as aunts and uncles are eligible. These individuals need not have kidney cancer, as they will be used for segregation analysis of suspected variants found in the proband; requesting DNA from relatives is required. Control Cohort: * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must not have a personal history of cancer, with the exception of nonmelanoma skin cancer, AND * Must not be a blood relative of any cases or controls enrolled in this study Exclusion Criteria: * Patients who, in the opinion of the primary MSKCC clinician or the investigator, have a condition that precludes their ability to provide an informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.