Application of Surgical Navigation System in Sentinel Lymph Node of Breast Cancer Research

Inclusion criteria: (Before the test, all the subjects required for meeting the entry requirements before they join the group)

* female patients;
* The preoperative core needle biopsy or open surgical excision biopsy diagnosis as breast cancer;
* tumor diameter ≤ 3cm;
* No clinical examination of suspicious axillary lymph node-positive;
* diagnosed clinical conditions can be directly surgery as I, II breast cancer patients;
* preoperative clinical or radiologic evidence without distant metastases (M0);
* signed informed consent.

Exclusion criteria: (Before the test, the subjects under any one of items to meet the requirements can not be enrolled)

* Sentinel lymph node biopsy history had received surgery or axillary area;
* multi-center breast cancer or multiple lesions;
* clinical axillary lymph node metastasis have been found;
* mammary area had received neoadjuvant chemotherapy or radiotherapy;
* inflammatory breast cancer;
* pregnancy;
* no personal freedom and independent civil capacity.

Exclusion criteria: (trials, subjects necessary to meet the requirements of any one item, exit the clinical trial research.)

* severe allergic reaction occurs;
* persistent allergic reaction;
* subjects were required to withdraw from a clinical trial;
* researchers consider it not appropriate to continue to participate in the clinical trial investigator.