Clinical trial · Interventional
The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum
The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum: A Prospective Randomized Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The following project deals with a Danish multicenter trial that evaluates the value of Laparoscopic Ultrasound examination (LUS) in laparoscopic surgery for colon and rectum cancer (CRC). The project "The value of laparoscopic ultrasound in patients undergoing laparoscopic resection for colon and rectum cancer. - A prospective randomized trial" is part of a ph.d- study at the University of Southern Denmark in collaboration with several surgical departments at hospitals in Southern Denmark. The primary purpose is to investigate whether the use of laparoscopic ultrasound examination (LUS) will change the stage of the tumor, lymph node and metastasis (TNM stage) and the surgical approach in patients undergoing laparoscopic surgery for colorectal cancer (CRC). As a secondary objective; an evaluation of the use of LUS will change the treatment strategy for the individual patient with CRC. As an other objective we wants to investigate whether the use of contrast enhanced ultrasound examination in connection with LUS procedure increases the number of detected liver metastases.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Liver Metastases | — | UNRESOLVED | — |
| Rectum Cancer | Rectal Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Lap+Lus | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Lap+Lus
- description
- The included patients randomly assigned either to the department's standard laparoscopic (Lap) surgery or standard laparoscopic surgery (lap) plus a LUS examination. In the intervention arm the intra-abdominal conditions are also assessed by laparoscopy, but then supplemented with a LUS examination of the primary tumor, liver and retroperitoneum. All the included patients are getting a CT scan of the abdomen after 3 months.
- interventionNames
- Device: Lap+Lus
- type
- NO_INTERVENTION
- label
- laparoscopic examination (Lap)
- description
- The included patients randomly assigned either to the department's standard laparoscopic (Lap) surgery or standard laparoscopic surgery (lap) plus a LUS examination. In the standard arm (Lap) the conditions at the abdomen is only assessed by laparoscopy immediately prior to the resection. All the included patients are getting a CT scan of the abdomen after 3 months.
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with colon and rectum cancer without known metastasis * Patients who gives informed consent * Patients who are referral to laparoscopic surgery Exclusion Criteria: * Patients who are not able to give informed consent * Patients who are under 18 of age Patients with known metastasis. * Patients who are allergic to contrast agents * Patients who are pregnant or lactating
References
Publications (1)
- DERIVEDEllebaek SB, Fristrup CW, Hovendal C, Qvist N, Bundgaard L, Salomon S, Stovring J, Mortensen MB. Randomized clinical trial of laparoscopic ultrasonography before laparoscopic colorectal cancer resection. Br J Surg. 2017 Oct;104(11):1462-1469. doi: 10.1002/bjs.10636. PMID 28895143