Clinical trial · Observational
Incidence and Risk Factors of Refeeding Syndrome
Incidence and Risk Factors of Refeeding Syndrome in Head and Neck Cancer Patients - An Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main objective of this observational survey was to determine the incidence rate of refeeding phenomena (RFF) (defined as any decline in p-phosphate) and RFS (defined as any decline in p-phosphate with additional development of any of the following clinical symptoms: oedema, confusion, dyspnoea, hypotension, arrhythmia, seizures) among recently admitted or referred HNC patients to the Department of Otorhinolaryngology for surgery. The second objective was to determine if informations at admittance could identify HNC patients at high risk of developing RFF and RFS.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer of the Head and Neck | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No intervention, only observation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Head -Neck cancer patients, no intervention
- interventionNames
- Other: No intervention, only observation
Primary outcomes (1)
- measure
- Decrease in plasma phosphate after start of feeding
- timeFrame
- 1 week
- description
- Plasma phosphate measured every day the initial day of feeding after admission
Secondary outcomes (1)
- measure
- Occurence of relevant clinical symptoms along with a decrease in plasma phosphate
- timeFrame
- 1 week
- description
- Daily registration of symptoms: oedema, confusion, dyspnoea, hypotension, arrhythmia, seizures
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Head and Neck Cancer Exclusion Criteria: * Not able to understand and speak Danish, having severe dementia and/or renal impairment (women: p-creatinine \> 180 μmol/l, men: p-creatinine \> 200 μmol/l).
References
Publications (1)
- DERIVEDRasmussen SO, Kristensen MB, Wessel I, Andersen JR. Incidence and Risk Factors of Refeeding Syndrome in Head and Neck Cancer Patients-An Observational Study. Nutr Cancer. 2016 Nov-Dec;68(8):1320-1329. doi: 10.1080/01635581.2016.1225103. Epub 2016 Sep 28. PMID 27682582