Clinical trial · Observational
Blood Collection From People With Ovarian Cancer
Collection of Blood From Patients With Ovarian, Primary Peritoneal or Fallopian Tube Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Background: * Monocytes are a type of white blood cell found in human blood. They help the immune system. Researchers have found that monocytes taken from the blood of healthy people can kill tumor cells. Now they want to know if monocytes taken from the blood of people with ovarian cancer can kill tumor cells. * In addition, native host anti-tumor cell mediated immune mechanisms may play a role in clinical outcome of epithelial ovarian cancer; data indicate that the presence of intra-tumoral CD3+ T-cells was shown to prognosticate improved outcome in advanced ovarian cancer. Furthermore, non-cellular components in the blood, such as exosomes, may influence outcome. Objective: \- To see if monocytes taken from the blood of people with ovarian cancer can kill tumor cells. Eligibility: \- Women 18 years and older with ovarian cancer. Design: * Participants will be screened with: * Medical history and physical exam. * Blood tests. * CT scan of the chest, abdomen, and pelvis and/or an MRI. For these scans, they will lie in a machine that takes pictures of their body. * A small amount of blood (two tubes) will be collected by needle during one visit.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer of the Ovary | Malignant Ovarian Neoplasm | ALIAS | 0.90 |
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
| Ovarian Neoplasms | Ovarian Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Cohort 1
- description
- Subjects w/ovarian, primary peritoneal or fallopian tube ca who are not currently on therapy and are screening for trials, being seen in consultation, or presenting for enrollment on a trial.
Primary outcomes (1)
- measure
- To obtain blood samples from patients with ovarian, primary peritoneal or fallopian tube cancer
- timeFrame
- Single blood collection upon enrollment
- description
- A collection of blood samples from patients with ovarian, primary peritoneal or fallopian tube cancer
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
* INCLUSION CRITERIA * Females greater than or equal to 18 years of age with histologically proven ovarian, primary peritoneal or fallopian tube cancer. * Currently not on therapy. Must be at least 2 weeks from prior therapy. * Ability and willingness to provide informed consent to participation. EXCLUSION CRITERIA \- Children are not eligible.
References
Publications (0)
Data not yet available