Clinical trial · Interventional
Evaluation of Preoperative Oral Rehydration Solution in Colectomy
Preoperative Oral Carbohydrate-rich Solution in Colorectal Cancer Patients: a Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): patient enrollment was failed.
Summary
Brief summary (as posted)
Elective colectomy procedures typically require bowel preparation starting 2 days prior to the surgery. Osmotic laxatives such as Colyte® are administered 2 days prior, and Nothing by mouth (NPO) is required 1 day prior to ensure no fecal residue is left in the bowel. Though it may ensure a cleaner and safer surgery, this longer period of starvation increases insulin resistance and may increase post-op complications. However, there is evidence that administration of oral rehydration solution(ORS) prior to surgery reduces insulin resistance. Our purpose is to evaluate the difference of insulin resistance in those who received ORS 1 day prior to surgery and those who did not.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Insulin Resistance | — | UNRESOLVED | — |
| Postoperative Complication | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Oral rehydration solution | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- ORS group
- description
- Oral rehydration solution (ORS) treated group
- interventionNames
- Dietary Supplement: Oral rehydration solution
- type
- NO_INTERVENTION
- label
- Non-ORS group
- description
- Oral rehydration solution (ORS) untreated group
Primary outcomes (1)
- measure
- Changes in HOMA-IR levels
- timeFrame
- 6hr, 24hr, 48hr
- description
- HOMA-IR = Insulin (μU/ml) X blood glucose (mg/dl) / 405 insulin and glucose levels are obtained 6hrs, 24hrs, 48hrs post-op Derive the value using the obtained sample variables into the HOMA-IR equation and comparison using statistical analytic methods
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * ASA grade I\~II (DM, CVA, COPD, ESRD, MI, TIA etc. excluded) * Age: adults age 19\~75 * Patients undergoing elective colon cancer surgery * Able to take the ORS per orally. Able to swallow without trouble of aspiration tendencies * BMI of less than 27.5 * Child-Turcotte-Pugh Classification score of less than 6 Exclusion Criteria: * emergency cases such as obstruction or perforation * food allergy * abdominal distension at present * prior gastric surgery
References
Publications (0)
Data not yet available