Clinical trial · Interventional
Corticospinal Excitability and Rehab in Knee Osteoarthritis
NCT02036866CI-TRIAL-00020190completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To determine differences in thigh muscle function in individuals with and without knee arthritis, and also determine the effectiveness of common physical therapy interventions on clinical and patient oriented outcomes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Knee Osteoarthritis | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No Intervention | Other | — | UNRESOLVED |
| Physical Therapy Exercises | Other | — | UNRESOLVED |
| Transcutaneous Electrical Nerve Stimulation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Physical Therapy Positive Expectation
- description
- The physical therapist will read a script indicating that the intervention is an effective treatment for knee osteoarthritis and is expected to reduce pain and improve strength. Patients are then instructed on the home exercise program and how to operate the TENS (transcutaneous electrical nerve stimulation) unit. The duration of intervention is 1 week during which patients will wear then wear the TENS unit for 8 hours per day and perform no more than 3 sets of 10 repetitions of the physical therapy exercises daily.
- interventionNames
- Other: Transcutaneous Electrical Nerve Stimulation
- Other: Physical Therapy Exercises
- type
- EXPERIMENTAL
- label
- Physical Therapy Neutral Expectation
- description
- The physical therapist will read a script indicating that the intervention may or may not be an effective treatment for knee osteoarthritis and may nor may not reduce pain and improve strength. Patients are then instructed on the home exercise program and how to operate the TENS unit. The duration of intervention is 1 week during which patients will wear then wear the TENS unit for 8 hours per day and perform no more than 3 sets of 10 repetitions of the physical therapy exercises daily.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Age 19-65 * Grade I or II knee Osteoarthritis confirmed by radiographs or other imaging and at least one of the following: * Age \> 50 years old * Morning stiffness \< 30 minutes * Crepitus * Meet at least 3 of 6 diagnostic criteria for osteoarthritis: * Age \> 50 years old * Morning stiffness \< 30 minutes * Crepitus * Bony tenderness * Bony enlargement * No palpable warmth Exclusion Criteria: * BMI \> 30 * History of traumatic spine or lower extremity injury within the last 6 months * Previous adverse reaction to electrical stimulation (i.e. burns or hypersensitivity) * Cardiac pacemaker * Metal implants in head * Current pregnancy * Neurological disorders * History of seizures * Unable to give consent or understand the procedures of this study
References
Publications (0)
Data not yet available
No reference posted for this study.