Clinical trial · Observational
High Resolution Magnetic Resonance Imaging in Patients With Brain Tumors
NCT02035852CI-TRIAL-00036308completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study will compare two different size MRI's of a brain tumor.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumor | Brain Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MRI | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Adult Gilomas
- interventionNames
- Other: MRI
Primary outcomes (1)
- measure
- Benefit of 7T MR imaging
- timeFrame
- Baseline and 6 month intervals after baseline
- description
- 1\. To determine the benefit of 7T MR imaging in brain tumor patients with regard to the improvement in resolution, as measured by the area of T2 FLAIR signal abnormality and the ability to detect abnormalities in vascular integrity. The benefit will be determined at a single time point as well as longitudinally for each patient at 6 month intervals.
Secondary outcomes (1)
- measure
- Vascular Integrity
- timeFrame
- Every 6 months, up to 12 months.
- description
- To determine if changes in vascular integrity at 7T can be correlated with tumor progression or transformation to high grade in patients with low grade gliomas.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Male or female, age 18 years or older * Patient must meet at least one of the four following criteria regarding brain tumor diagnosis: * Histological diagnosis of a brain tumor * Histological diagnosis of systemic cancer and brain MR imaging suggestive of metastatic disease to the brain * Pre-operative brain MR imaging suggestive of a brain tumor * Radiographic diagnosis of brain tumor in an inoperable location (e.g., brainstem) * Patient able and willing to provide informed consent * Karnofsky Performance status \> 70% * Life expectancy greater than 3 months * Negative serum or urine pregnancy test or child bearing potential terminated by surgery, radiation, menopause or current use of two approved methods of birth control * Patients who are excluded from 7T MR imaging because of titanium implants that are not yet established to be safe at 7T remain eligible for the imaging at 3T \* Spanish speaking participants will be enrolled for this study Exclusion Criteria: * Body weight \>137 Kg (300 lbs) * Patient unable to provide informed consent * Karnofsky Performance status \< 70% * Patients who are claustrophobic or have other contraindications to MRI, such as implanted pacemaker device vascular clips, surgical clips, prosthetic valves, pacemakers, otologic implants * NYHA class III and IV congestive heart failure * Psychiatric or addictive disorders that preclude obtaining informed consent * Unstable angina * Sexually active patients of childbearing potential not using a reliable contraceptive method * Pregnant or lactating women * Women of childbearing potential who refuse a pregnancy test (performed during screening)
References
Publications (0)
Data not yet available
No reference posted for this study.