Clinical trial · Interventional
EndoCuff-assisted Versus Standard Colonoscopy for Adenoma Detection
A Randomized Controlled Study to Compare EndoCuff-assisted With Standard Colonoscopy for the Detection of Adenomas
NCT02034929CI-TRIAL-00031972completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The EndoCuff is novel flexible cuff that can be attached to the distal tip of the colonoscope and helps to flatten large mucosal folds during withdrawal. The study hypothesis is that the use of the Endocuff (EC) increases the adenoma detection rate during colonoscopy. The study purpose is to compare EC-assisted colonoscopy with standard colonoscopy for polyp detection.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adenoma | Adenoma | ONTOLOGY_EXACT | 0.98 |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Polyp | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EndoCuff-assisted colonoscopy | Device | — | UNRESOLVED |
| Standard colonoscopy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Endocuff-assisted colonoscopy
- description
- Endocuff-assisted colonoscopy
- interventionNames
- Device: EndoCuff-assisted colonoscopy
- type
- ACTIVE_COMPARATOR
- label
- Standard colonoscopy
- description
- Standard Colonoscopy
- interventionNames
- Device: Standard colonoscopy
Primary outcomes (1)
- measure
- adenoma detection rate
- timeFrame
- 25 minutes
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: indication for colonoscopy (screening, surveillance, diagnostic) ager ≥ 18 years ability to give informed consent Exclusion Criteria: * pregnancy * age\<18 years * known colonic strictures * chronic inflammatory bowel disease * active inflammation * s/p colonic resection
References
Publications (1)
- DERIVEDFloer M, Biecker E, Fitzlaff R, Roming H, Ameis D, Heinecke A, Kunsch S, Ellenrieder V, Strobel P, Schepke M, Meister T. Higher adenoma detection rates with endocuff-assisted colonoscopy - a randomized controlled multicenter trial. PLoS One. 2014 Dec 3;9(12):e114267. doi: 10.1371/journal.pone.0114267. eCollection 2014. PMID 25470133