Clinical trial · Observational
Character Traits and Stress in Suspected Prostate Cancer
A Questionnaire Study by Elevated Prostate Specific Antigen (PSA): Do Men Where Subsequent Assessment Shows Prostate Cancer, Higher Levels of Neuroticism and Stress Compared to Those Who do Not Get the Diagnosis?
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Stopped by the sponsor due to discrepancies in the recruitment process.
Summary
Brief summary (as posted)
It has previously been reported that men with prostate cancer are 1 ) reduced quality of life after diagnosis and treatment, 2 ) neuroticism increases the reduction in QoL related to treatment side effects, and 3) often have very involved and active spouses who seems to have been handed over / taken over parts of the men's responsibility for their own health. We postulate herein a new hypothesis that the stress level is elevated when harbouring undetected prostate cancer. We will investigate whether those who are diagnosed with prostate cancer already in beforehand have an increased degree of masculine stress ( experience of not living up to their own perception of the ideal man ) and neuroticism in the typology. We will examine different personality and QoL questionnaires for patients with elevated PSA, and compare those whose clinical assessment later reveals prostate cancer, with three control groups: 1) men with elevated PSA who are not diagnosed with prostate cancer, 2) men with normal PSA treated for benign prostate enlargement and 3) patient with substantial risk of colorectal cancer (CRC) who undergo colonoscopy, with regard to increased level of masculine stress and the personality trait neuroticism.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostatic Diseases | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- MGRSS questionnaire
- timeFrame
- 2 years
- description
- The profile of the answering patterns will be compared to baseline using psychiatric and statistical evaluation.
- measure
- Testosterone
- timeFrame
- 2 years
- description
- Testosterone at baseline and 2 years will be related to wether the patient has confirmed cancer or not.
- measure
- Cholesterol
- timeFrame
- 2 years
- description
- Cholesterol at baseline and 2 years will be related to wether the patient has confirmed cancer or not.
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Men who be referred a new urological outpatient and satisfy the following: * Wanted examined because of elevated PSA * Not strong family history of prostate cancer * It is taken biopsy as part of routine investigation. 2. Control group: Men referred to urological outpatient clinic, and who satisfy the following * urination complaints * Normal PSA * examination shows prostate size\> 40cc 3. Control group: Men first time referred urological / gastroenterological outpatient clinic, and which satisfy the following \-- symptoms that might indicate cancer suspicion in colorectum 4. Age\> 40 years and \<75 years Exclusion criteria: 1. known prostate cancer 2. Reduced consent 4 Familial occurrence of prostate cancer (one or more 1st degree relatives with CaP)
References
Publications (0)
Data not yet available