Clinical trial · Interventional
Loop-tipped Guidewire in Selective Biliary Cannulation
Loop-tipped Guidewire in Selective Biliary Cannulation: a Prospective, Randomized, Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
1. Background * Advanced guidewires with a U-shaped tip could effectively cross the long or multi-occlusive segment smoothly and go into the distal outflow vessel. * The guidewire looping technique is a safe and effective method for the recanalization of the occluded lesions in infrapopliteal vessels. 2. Objective - To compare the performance a loop-tipped guidewire with a straight-tipped guidewire in achieving successful deep biliary cannulation. 3. Design \- Prospective randomized trial. 4. Setting: \- Tertiary-care medical center 5. Patients \- This study will involve 192 patients with biliary diseases which require endoscopic retrograde cholangiopancreatography. 6. Intervention - Cannulation of bile duct by using a loop-tipped guidewire or a straight-tipped guidewire 7. Main outcome measurements - Compare the cannulation success rate, the duration of the cannulation, immediate and late complications.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ampullary Tumor | — | UNRESOLVED | — |
| Bile Duct Cancer | Malignant Bile Duct Neoplasm | CURATED_BROADER | 0.80 |
| Choledocholithiasis | — | UNRESOLVED | — |
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biliary cannulation with loop guidewire | Device | — | UNRESOLVED |
| Biliary cannulation with straight guidewire | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Loop guidewire
- description
- This study has two arms. We will compare the performance of a loop-tipped guidewire with a straight-tipped guidewire in achieving successful deep biliary cannulation with loop guidewire.
- interventionNames
- Device: Biliary cannulation with loop guidewire
- type
- ACTIVE_COMPARATOR
- label
- Straight guidewire
- description
- This study has two arms. We will compare the performance of a loop-tipped guidewire with a straight-tipped guidewire in achieving successful deep biliary cannulation with straight guidewire.
- interventionNames
- Device: Biliary cannulation with straight guidewire
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * age \> 19 and ability to consent * no evidence of significant cardiopulmonary or medical comorbidities precluding participation Exclusion Criteria: * Known gastroduodenal anatomic abnormalities * Coagulation disorders (international normalized ratio \> 1.5 or platelet count \< 50000 cells/cubic millimeter) * Prior gastric surgery,endoscopic retrograde cholangiopancreatography * Pregnancy
References
Publications (0)
Data not yet available