Clinical trial · Interventional
Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study
NCT02025023CI-TRIAL-00043233CTSunknownPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chalazion | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 5-fluorouracil Injection | Drug | Fluorouracil | ALIAS |
| Incision and Curettage | Procedure | — | UNRESOLVED |
| Triamcinolone Acetonide | Drug | — | UNRESOLVED |
| Triamcinolone Acetonide/5-fluorouracil mixture | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- Incision and Curettage
- description
- A vertical incision over the area of chalazion will be done. Inflammatory material will be removed and the chalazion capsule will be excised.
- interventionNames
- Procedure: Incision and Curettage
- type
- ACTIVE_COMPARATOR
- label
- Injection of Triamcinolone Acetonide
- description
- 0.1 ml of triamcinolone is injected directly in the chalazion.
- interventionNames
- Drug: Triamcinolone Acetonide
- Procedure: Incision and Curettage
- type
- ACTIVE_COMPARATOR
- label
- Injection of 5-fluorouracil
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Single or multiple chalazia in a single eyelid Exclusion Criteria: * Chalazia present for less than one month and no previous injection or incision and curettage
References
Publications (0)
Data not yet available
No reference posted for this study.