Clinical trial · Observational
Magnetic Resonance Imaging (MRI) in Motion
Magnetic Resonance Imaging ( MRI) for Radiation Therapy Treatment Planning Evaluation of Lung, Liver and Pancreatic Motion.
NCT02019199CI-TRIAL-00028549completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is a research initiative established to explore the use of magnetic resonance imaging (MRI) as a tool for detecting organ motion as it pertains to planning radiation therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Liver Cancer, Lung Cancer, Pancreatic Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.85 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- To evaluate the accuracy, robustness, and efficacy of MRI for tumor motion measurement.
- timeFrame
- During MRI approx 1 hour
- description
- MRI and CT ( all subjects will have a standard of care CT scan) data in DICOM format will be collected for analysis using commercial or customized - developed software. Image quality will be assessed based on signal-to-noise (SNR), contrast-to-noise ratio (CNR), and the presence of image artifacts. Data to be computed include, but are not limited to, tumor volumes (gross tumor volume, internal target volume, planning target volume, etc.), tumor motion parameters (range, trajectory, frequency, variation, probability distribution, etc.), and treatment plan parameters (target coverage, dose-volume-histogram, etc.).
- measure
- Tumor volume
- timeFrame
- During MRI approx 1 hour
- description
- Free breathing/breath-hold MRI will be compared to free breathing/breath-hold CT
- measure
- Tumor contrast-to-noise ratio (CNR)
- timeFrame
- During MRI approx 1 hour
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 21 * Patients with primary or metastatic tumors in the lungs, liver, or pancreas * Patients undergoing a planning CT scan in the Department of Radiation Oncology with tumor motion assessment - planning 4D-CT ordered by the treating Radiation Oncologist * Signed, specific informed consent prior to study entry Exclusion Criteria: * Any condition for which a MRI procedure is contraindicated including presence of metallic material in the body, such as pacemakers, non- MRI compatible surgical clips, shrapnel, etc * Pregnant or breast-feeding women * Subjects who have difficulty lying flat on their back for extended periods of time
References
Publications (0)
Data not yet available
No reference posted for this study.