Clinical trial · Interventional
Pulmonary Rehabilitation in Improving Lung Function in Patients With Locally Advanced Non-Small Cell Lung Cancer Undergoing Chemoradiation
Pulmonary Rehabilitation in Locally Advanced Non-Small Cell Lung Cancer
NCT02017925CI-TRIAL-00026954withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized clinical trial studies pulmonary rehabilitation in improving lung function in patients with locally advanced non-small cell lung cancer undergoing chemoradiation. Individualized exercise rehabilitation programs may reduce breathing problems and improve quality of life in patients with non-small cell lung cancer. It is not yet known whether pulmonary rehabilitation is more effective when started during or after cancer treatment.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cachexia | — | UNRESOLVED | — |
| Fatigue | — | UNRESOLVED | — |
| Pulmonary Complications | — | UNRESOLVED | — |
| Radiation Toxicity | — | UNRESOLVED | — |
| Recurrent Non-small Cell Lung Cancer | Lung Non-Small Cell Carcinoma | CURATED_BROADER | 0.78 |
| Stage IIIA Non-small Cell Lung Cancer | Lung Non-Small Cell Carcinoma | CURATED_BROADER | 0.78 |
| Stage IIIB Non-small Cell Lung Cancer | Lung Non-Small Cell Carcinoma | CURATED_BROADER | 0.78 |
| Stage IV Non-small Cell Lung Cancer | Lung Non-Small Cell Carcinoma | CURATED_BROADER | 0.78 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| exercise intervention | Behavioral | — | UNRESOLVED |
| pulmonary complications management/prevention | Procedure | — | UNRESOLVED |
| quality-of-life assessment | Procedure | — | UNRESOLVED |
| questionnaire administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I (early intervention)
- description
- Beginning within 2 weeks of starting chemoradiation, patients undergo an individualized rehabilitation program comprising aerobic exercise and strength training, including treadmill walking, stationary bicycle, NU-Step, upper body resistance training and breathing retraining, 3 times per week for 8 weeks (36 sessions).
- interventionNames
- Behavioral: exercise intervention
- Procedure: pulmonary complications management/prevention
- Procedure: quality-of-life assessment
- Other: questionnaire administration
- type
- EXPERIMENTAL
- label
- Arm II (late intervention)
- description
- Beginning 1 month after completion of chemoradiation, patients undergo an individualized exercise rehabilitation program as in Arm I.
- interventionNames
- Behavioral: exercise intervention
- Procedure: pulmonary complications management/prevention
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who have been diagnosed with locally advanced unresectable NSCLC undergoing definite chemo-radiation with curative intent * Patients must be able to sign informed consent * Patients who qualify for pulmonary rehabilitation as part of the standard of care and are covered by medical insurance * Patients must be able to ambulate a minimum of 100 feet prior to enrollment in pulmonary rehab * Patients must be willing and able to travel to the pulmonary rehabilitation site at the Morehouse Medical Plaza Exclusion Criteria: * Tumor resection candidates * If survival is deemed less than 6 months for any medical condition * If they have angina or unstable coronary disease * Congestive heart failure refractory to medical management * Malignancy with bone instability * Inmates
References
Publications (0)
Data not yet available
No reference posted for this study.