Clinical trial · Interventional
Effect of Physical Therapy on Breast Cancer Related Lymphedema
Effect of Physical Therapy on Breast Cancer Related Lymphedema; A Multicenter, Randomized, Single-blind, Equivalence Trial
NCT02015897CI-TRIAL-00063551completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study is to investigate if Complete Decongestive Therapy is equally effective whether it includes manual lymphatic drainage or not in the treatment of lymphoedema among patients with breast cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Lymphoedema | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Physical TherapyA | Procedure | — | UNRESOLVED |
| Physical TherapyB | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Physical TherapyB
- description
- Group B
- interventionNames
- Procedure: Physical TherapyA
- type
- PLACEBO_COMPARATOR
- label
- Physical TherapyA
- description
- Group A
- interventionNames
- Procedure: Physical TherapyB
Primary outcomes (1)
- measure
- The percentage volume reduction of lymphoedema (%)
- timeFrame
- 7 months
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * The diagnose breast cancer regardless of date for operation and identified lymphoedema * Precede ultrasonic scanning of axilla in order to exclude local relapse * Lymphoedema \> 2 cm i.e. stage II-III * Completed radiotherapy and/or chemotherapy at least 2 months prior inclusion Exclusion Criteria: * Relapse of breast cancer * Untreated infection * Untreated heart failure * Untreated renal failure * Untreated deep venous thrombosis in the arm * Unable to participate in physiotherapy treatment and/or not able to understand instructions
References
Publications (2)
- DERIVEDTambour M, Holt M, Speyer A, Christensen R, Gram B. Manual lymphatic drainage adds no further volume reduction to Complete Decongestive Therapy on breast cancer-related lymphoedema: a multicentre, randomised, single-blind trial. Br J Cancer. 2018 Nov;119(10):1215-1222. doi: 10.1038/s41416-018-0306-4. Epub 2018 Oct 24. PMID 30353049
- DERIVEDTambour M, Tange B, Christensen R, Gram B. Effect of physical therapy on breast cancer related lymphedema: protocol for a multicenter, randomized, single-blind, equivalence trial. BMC Cancer. 2014 Apr 3;14:239. doi: 10.1186/1471-2407-14-239. PMID 24708851