Clinical trial · Observational
Characterization of a Prospective Cohort of Women With PCOS
Metabolic and Endocrinological Characterization of a Prospective Cohort of Women With PCOS
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. PCOS is characterized by increase levels of testosterone, unwanted hair growth, adiposity, irregular menstrual cycle, and infertility. PCOS is associated with diabetes mellitus and cardiovascular diseases. Women with PCOS are reported to have increased levels of stress hormones, which may be associated with decreased quality of life. Increased testosterone levels in women may decrease the risk of osteoporosis. The aim of the present study is to measure levels of stress hormones in urine and describe quality of life using questionnaires. In addition we aim to characterize body composition and bone architecture using DXA and ExtremeCT. As part of the project, a Biobank with fasting blood samples from participants is established.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- PCOS
- description
- Women fulfilling at least two of the three Rotterdam criteria for PCOS, including * Irregular menstrual cycle * Clinical/biochemical hyperandrogenemia * Polycystic ovaries
Primary outcomes (1)
- measure
- bone mass density (BMD)
- timeFrame
- baseline
- description
- BMD measured by DXA scans and ExtremeCT scans.
Secondary outcomes (1)
- measure
- Stress hormones
- timeFrame
- Baseline
- description
- Measurement of cortisol and steroid metabolites in 24 hour urine samples
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * PCOS Exclusion Criteria: * pregnancy
References
Publications (0)
Data not yet available