Meloxicam vs Placebo for Mobilization

Inclusion Criteria:

* Participants must meet the following criteria on screening examination to be eligible to participate in the study:
* Patients with hematologic malignancies for whom autologous stem cell transplantation is deemed clinically appropriate. Patients participating in this study are patients who are going for their first attempt at stem cell mobilization.
* Non-Hodgkin's lymphoma, or Hodgkin's lymphoma: refractory/relapsed but chemosensitive disease. Patients with CR or PR will be eligible for this protocol.

The designation of PR requires all of the following:

* At least a 50% decrease in sum of the product of the diameters (SPD) of up to six of the largest dominant nodes or nodal masses. These nodes or masses should be selected according to all of the following: they should be clearly measurable in at least 2 perpendicular dimensions; if possible they should be from disparate regions of the body; and they should include mediastinal and retroperitoneal areas of disease whenever these sites are involved.
* No increase should be observed in the size of other nodes, liver, or spleen.
* Splenic and hepatic nodules must regress by ≥ 50% in their SPD or, for single nodules, in the greatest transverse diameter.
* With the exception of splenic and hepatic nodules, involvement of other organs is usually assessable and no measurable disease should be present.
* Bone marrow assessment is irrelevant for determination of a PR if the sample was positive before treatment. However, if positive, the cell type should be specified (eg, large-cell lymphoma or small neoplastic B cells). Patients who achieve a CR by the above criteria, but who have persistent morphologic bone marrow involvement will be considered partial responders. Multiple myeloma in first or second remission. Patients with CR or VGPR will be eligible for this protocol. \[VGPR: Serum and urine M-protein detectable by immunofixation only but not on electrophoresis or 90% or greater reduction in serum M-protein plus urine M-protein level \<100mg per 24 h\]
* Ages 18-75 years
* ECOG performance status of 0, 1, or 2.
* Ability to understand and the willingness to sign a written informed consent
* Patients on NSAIDs will be eligible only when they are off NSAIDs for a month.

Exclusion Criteria:

* Participants who exhibit any of the following conditions at screening will not be eligible for admission into the study.
* Cardiac disease: symptomatic congestive heart failure or RVG or echocardiogram determined left ventricular ejection fraction of \< 45%, active angina pectoris, or uncontrolled hypertensionParticipants may not be receiving any other study agents.
* Pulmonary disease: severe chronic obstructive lung disease, or symptomatic restrictive lung disease, or corrected DLCO of \< 50% of predicted.
* Renal disease: serum creatinine \> 2.0 mg/dl.
* Hepatic disease: SGOT or SGPT \> 3 x normal; serum bilirubin \>2.0 mg/dl that is not due to Gilbert's syndrome or hemolysis
* Uncontrolled infection.
* Pregnancy or lactation
* Patients with NSAIDs allergies, including patients who have experienced a prior GI bleed due to NSAIDs will be excluded. Patients who have had a recent GI bleed less than 2 weeks ago will be excluded. Patients who are on therapeutic dose anticoagulants will be excluded from this protocol.