Clinical trial · Observational
A Pilot Trial to Determine the Extent of Inter- and Intra-Treatment Organ Motion Using Active Breathing Control Device (ABC) in Patients With Pancreatic Cancer
NCT01986738CI-TRIAL-00026262completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a study to assess the motion of pancreatic tumors during radiation therapy using Computed Tomography (CT) Scans and an Active Breathing Control (ABC) Device.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Active Breathing Control Device (ABC) | Device | — | UNRESOLVED |
| Computed Tomography Scan (CT) | Device | — | UNRESOLVED |
| Standard Radiation Therapy | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Radiation Treatment
- description
- Patients undergoing standard of care radiation treatment with Active Breathing Control (ABC)
- interventionNames
- Radiation: Standard Radiation Therapy
- Device: Active Breathing Control Device (ABC)
- Device: Computed Tomography Scan (CT)
Primary outcomes (2)
- measure
- Distance traveled by the pancreatic tumor during radiation treatment using Computed Tomography (CT) Scans and an Active Breathing Control (ABC) Device
- timeFrame
- Weeks -3 to -1, Week 1, Week 3, Week 5
- description
- A marker (implanted near the radiation site, prior to treatment, as a point of reference) will be noted in space on an x, y and z plane using a CT scan. The excursion of this marker during treatment will be determined and the distance traveled, as well as the overall vector (distance and magnitude), will be calculated. Later scans will assess changes in the ability to calculate distance traveled and overall vector of travel.
- measure
- Distance traveled by the pancreatic tumor between radiation treatments using Computed Tomography (CT) Scans and an Active Breathing Control (ABC) Device
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients ≥ 18 years of age * A working diagnosis (with or without histologic confirmation) of pancreatic cancer * A plan to treat with radiotherapy (or chemoradiotherapy) * Patients must have fiducial marker(s) endoscopically placed within the pancreas for clinical treatment. Exclusion Criteria: * Previous abdominal radiotherapy. * Patients with a history of major abdominal surgery. * Patients who are pregnant.
References
Publications (0)
Data not yet available
No reference posted for this study.